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adding back todos
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pnavada committed Nov 26, 2023
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24 changes: 12 additions & 12 deletions src/eliater/network_validation.py
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If the percentage of failed tests is higher than the user expects, additional experiments
is required to change the model.
T. How does the user set their expectation? This kind of text gives no help to someone reading this for the
T. first time that wants to understand how to use this or why to use it
.. todo:: How does the user set their expectation? This kind of text gives no help to someone reading this for the
.. todo:: first time that wants to understand how to use this or why to use it
T Cell Signalling Example
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in [Sachs2005]_. It models the molecular mechanisms and regulatory processes involved
in T cell activation, proliferation, and function.
T. what about explanation of data?
.. todo:: what about explanation of data?
.. figure:: img/signaling.png
:width: 200px
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The results show that out of 35 cases, 1 failed. The failed test is
the conditional independence between P38 and PIP2, given PKC, with a p-value of 0.00425.
T. link all mentions of biological entities to HGNC or UniProt pages
.. todo:: link all mentions of biological entities to HGNC or UniProt pages
Finding False Negatives
-----------------------
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There are three main reasons that the result of the test may be false negative or false positive:
1. T. 1 sentence summary of scenario 1
2. T. 1 sentence summary of scenario 2
3. T. 1 sentence summary of scenario 3
1. .. todo:: 1 sentence summary of scenario 1
2. .. todo:: 1 sentence summary of scenario 2
3. .. todo:: 1 sentence summary of scenario 3
T. give meaningful names for all point headers
.. todo:: give meaningful names for all point headers
False Negatives Scenario 1
~~~~~~~~~~~~~~~~~~~~~~~~~~
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Note that this module employs traditional tests where the null hypothesis is conditional independence.
T. demonstrate an example
.. todo:: demonstrate an example
False Negatives Scenario 2
~~~~~~~~~~~~~~~~~~~~~~~~~~
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utilizing the Pearson test yields a test statistic that adheres to the Normal distribution. If these
assumptions are not satisfied by the data, the outcomes may lead to both false positives and false negatives.
T. demonstrate an example
.. todo:: demonstrate an example
False Negatives Scenario 3
~~~~~~~~~~~~~~~~~~~~~~~~~~
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as dependent. Hence, chances of false negatives increases, i.e., a pair of variables that are
conditionally independent, be concluded as conditional dependent by the test.
T. this can be one sentence (super wordy), but also needs a second sentence answering the question: "why?"
.. todo:: this can be one sentence (super wordy), but also needs a second sentence answering the question: "why?"
T. don't use first person in a demo. Just use active verbs about the demo itself
.. todo:: don't use first person in a demo. Just use active verbs about the demo itself
We demonstrate this third phenomena below using the following example graph, observational data
(simulated specifically for this graph using
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