geneontology · kltm · Jul 14, 2022 · Jun 9, 2022 · Jun 18, 2022 · Jun 30, 2022
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@@ -0,0 +1,164 @@
+@prefix : <http://model.geneontology.org/SYNGO_1117#> .
+@prefix owl: <http://www.w3.org/2002/07/owl#> .
+@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
+@prefix xml: <http://www.w3.org/XML/1998/namespace> .
+@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
+@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
+@base <http://model.geneontology.org/SYNGO_1117> .
+
+<http://model.geneontology.org/SYNGO_1117> rdf:type owl:Ontology ;
+                                            <http://purl.org/dc/elements/1.1/title> "Grik1_MF_1117"^^xsd:string ;
+                                            <http://geneontology.org/lego/modelstate> "production"^^xsd:string ;
+                                            <http://purl.org/dc/elements/1.1/date> "2018-06-29"^^xsd:string ;
+                                            <https://w3id.org/biolink/vocab/in_taxon> "http://purl.obolibrary.org/obo/NCBITaxon_10116"^^xsd:string ;
+                                            rdfs:comment """Rationale: Kainate receptor GluR5 (=GRIK1).
+
+rule: NAS_MFCC-BP
+rationale:
+Protein has ligand-gated ion channel receptor activity and is localized in the presynaptic membrane (shown with high-resolution technique). The inference to term ligand-gated ion channel activity involved in regulation of presynaptic membrane potential (GO:0099507) is trivial and non-controversial.
+Pinf_CC:
+[P22756] SyNGO ID 1114 (PMID:16360275, EM). Experimental description: Isolation and expression of GluR-5 clones
+ForPCR (MullisandFalooona, 1987),oligonucleotideprimersandreaction conditionswereasdescribed(Keinanenetal.,1990).RatforebraincDNA was used as a template. The PCR product (- 500 bp) was gel-purified, cleaved with EcoRI and KpnI, subcloned into doubly cut M13mpl9 RF- DNA (Yanisch-Perronetal.,1985)andsequenced(Sangeretal.,1977). A PCR-generatedDNA fragmentofaGluR-5specificM 13subclonewas internalylabelledwith[3P]dCTPtoaspecificactivityof2x 109/Igand usedasaprobetoscreenaratforebraincDNA libraryconstructedinX- Zap (Stratagene). Five independent cDNAs from these screens were subclonedintopBluescriptSK plasmidvectors(Stratagene,CA) orM13mpl8 andmpl9RF-DNA (Yanisch-Perronetal.,1985)andthesesubcloneswere used for sequence analysis (Sanger et al., 1977). Expression constructs of GluR-5-2 specifying different C-termini were engineered by subcloning 3' BamnHI-AoI or BamHI-EcoRI fragments encoding C-termini of GluR-5-2aor-2-c,respectively,anda5'HindLH-BamHI fragmentdirectly intoamammalianexpressionvectorwithaCMV promoter(Gormanetal.,
+1990).TheheterogeneityconcerningglutamineandargininecodonsinTM2 wasgeneratedbyexchanginga400bpBspEI-MscIfragmentcoveringTM regionsItoImofeditedandnon-editedGIuR-5cDNA clones. Theconstructs wereusedtotransfecthumanembryonickidneycels293(ATCC CRL 1573)asdescribed(ChenandOkayama, 1987;Pritcheletal.,1989).These were subjected to binding studies and electrophysiology."""^^xsd:string ;
+                                            <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+                                            <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string ;
+                                            <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string .
+
+#################################################################
+#    Annotation properties
+#################################################################
+
+###  http://geneontology.org/lego/evidence
+<http://geneontology.org/lego/evidence> rdf:type owl:AnnotationProperty .
+
+
+###  http://purl.org/dc/elements/1.1/contributor
+<http://purl.org/dc/elements/1.1/contributor> rdf:type owl:AnnotationProperty .
+
+
+###  http://purl.org/dc/elements/1.1/date
+<http://purl.org/dc/elements/1.1/date> rdf:type owl:AnnotationProperty .
+
+
+###  http://purl.org/dc/elements/1.1/source
+<http://purl.org/dc/elements/1.1/source> rdf:type owl:AnnotationProperty .
+
+
+###  http://purl.org/pav/providedBy
+<http://purl.org/pav/providedBy> rdf:type owl:AnnotationProperty .
+
+
+#################################################################
+#    Object Properties
+#################################################################
+
+###  http://purl.obolibrary.org/obo/RO_0002333
+<http://purl.obolibrary.org/obo/RO_0002333> rdf:type owl:ObjectProperty .
+
+
+#################################################################
+#    Classes
+#################################################################
+
+###  http://identifiers.org/rgd/2732
+<http://identifiers.org/rgd/2732> rdf:type owl:Class .
+
+
+###  http://purl.obolibrary.org/obo/ECO_0000303
+<http://purl.obolibrary.org/obo/ECO_0000303> rdf:type owl:Class .
+
+
+###  http://purl.obolibrary.org/obo/ECO_0006013
+<http://purl.obolibrary.org/obo/ECO_0006013> rdf:type owl:Class .
+
+
+###  http://purl.obolibrary.org/obo/ECO_0006063
+<http://purl.obolibrary.org/obo/ECO_0006063> rdf:type owl:Class .
+
+
+###  http://purl.obolibrary.org/obo/ECO_0007695
+<http://purl.obolibrary.org/obo/ECO_0007695> rdf:type owl:Class .
+
+
+###  http://purl.obolibrary.org/obo/GO_0099507
+<http://purl.obolibrary.org/obo/GO_0099507> rdf:type owl:Class .
+
+
+#################################################################
+#    Individuals
+#################################################################
+
+###  http://model.geneontology.org/SYNGO_111707743ed6-872a-4ac4-babd-6151e73a471b
+<http://model.geneontology.org/SYNGO_111707743ed6-872a-4ac4-babd-6151e73a471b> rdf:type owl:NamedIndividual ,
+                                                                                        <http://purl.obolibrary.org/obo/ECO_0006063> ;
+                                                                               <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string ,
+                                                                                                                             "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/date> "2022-05-12"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/source> "PMID:1373382"^^xsd:string ;
+                                                                               <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string .
+
+
+###  http://model.geneontology.org/SYNGO_1117415d3124-bccf-4cb3-a408-29283a4640e0
+<http://model.geneontology.org/SYNGO_1117415d3124-bccf-4cb3-a408-29283a4640e0> rdf:type owl:NamedIndividual ,
+                                                                                        <http://purl.obolibrary.org/obo/ECO_0000303> ;
+                                                                               <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string ,
+                                                                                                                             "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/date> "2022-05-12"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/source> "PMID:1373382"^^xsd:string ;
+                                                                               <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string .
+
+
+###  http://model.geneontology.org/SYNGO_11175b35849c-28e3-434a-8ffe-578e3300b7a7
+<http://model.geneontology.org/SYNGO_11175b35849c-28e3-434a-8ffe-578e3300b7a7> rdf:type owl:NamedIndividual ,
+                                                                                        <http://purl.obolibrary.org/obo/GO_0099507> ;
+                                                                               <http://purl.obolibrary.org/obo/RO_0002333> <http://model.geneontology.org/SYNGO_111792435732-c5d0-4fd5-ac80-625c174287a2> ;
+                                                                               <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string ,
+                                                                                                                             "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/date> "2022-05-12"^^xsd:string ;
+                                                                               <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string .
+
+[ rdf:type owl:Axiom ;
+   owl:annotatedSource <http://model.geneontology.org/SYNGO_11175b35849c-28e3-434a-8ffe-578e3300b7a7> ;
+   owl:annotatedProperty <http://purl.obolibrary.org/obo/RO_0002333> ;
+   owl:annotatedTarget <http://model.geneontology.org/SYNGO_111792435732-c5d0-4fd5-ac80-625c174287a2> ;
+   <http://geneontology.org/lego/evidence> <http://model.geneontology.org/SYNGO_111707743ed6-872a-4ac4-babd-6151e73a471b> ,
+                                           <http://model.geneontology.org/SYNGO_1117415d3124-bccf-4cb3-a408-29283a4640e0> ,
+                                           <http://model.geneontology.org/SYNGO_11177875e3ef-1c84-4e90-a4aa-46de94119d05> ,
+                                           <http://model.geneontology.org/SYNGO_1117d695e236-1190-4621-84c5-b6070d1de406> ;
+   <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string ,
+                                                 "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+   <http://purl.org/dc/elements/1.1/date> "2022-05-12"^^xsd:string ;
+   <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string
+ ] .
+
+
+###  http://model.geneontology.org/SYNGO_11177875e3ef-1c84-4e90-a4aa-46de94119d05
+<http://model.geneontology.org/SYNGO_11177875e3ef-1c84-4e90-a4aa-46de94119d05> rdf:type owl:NamedIndividual ,
+                                                                                        <http://purl.obolibrary.org/obo/ECO_0007695> ;
+                                                                               <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string ,
+                                                                                                                             "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/date> "2022-05-12"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/source> "PMID:1373382"^^xsd:string ;
+                                                                               <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string .
+
+
+###  http://model.geneontology.org/SYNGO_111792435732-c5d0-4fd5-ac80-625c174287a2
+<http://model.geneontology.org/SYNGO_111792435732-c5d0-4fd5-ac80-625c174287a2> rdf:type owl:NamedIndividual ,
+                                                                                        <http://identifiers.org/rgd/2732> ;
+                                                                               <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string ,
+                                                                                                                             "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/date> "2022-05-12"^^xsd:string ;
+                                                                               <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string .
+
+
+###  http://model.geneontology.org/SYNGO_1117d695e236-1190-4621-84c5-b6070d1de406
+<http://model.geneontology.org/SYNGO_1117d695e236-1190-4621-84c5-b6070d1de406> rdf:type owl:NamedIndividual ,
+                                                                                        <http://purl.obolibrary.org/obo/ECO_0006013> ;
+                                                                               <http://purl.org/dc/elements/1.1/contributor> "http://orcid.org/0000-0001-9425-2935"^^xsd:string ,
+                                                                                                                             "http://orcid.org/0000-0002-2514-0216"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/date> "2022-05-12"^^xsd:string ;
+                                                                               <http://purl.org/dc/elements/1.1/source> "PMID:1373382"^^xsd:string ;
+                                                                               <http://purl.org/pav/providedBy> "https://syngo.vu.nl"^^xsd:string .
+
+
+###  Generated by the OWL API (version 4.2.7.20161016-0911) https://github.com/owlcs/owlapi