Apply Jakob's suggestion

src/coreclr/jit/lower.cpp

@@ -5552,13 +5552,15 @@ GenTree* Lowering::LowerDelegateInvoke(GenTreeCall* call)
     BlockRange().InsertBefore(call, newThisAddr, newThis, thisArgNode);
 
 #if !defined(TARGET_XARCH)
-    // Keep delegate alive if the target can't do an indirect call with an immediate operand
-    // and only in fully interruptible code.
     if (comp->GetInterruptible())
     {
-        GenTree* baseClone     = comp->gtCloneExpr(base);
-        GenTree* keepBaseAlive = comp->gtNewKeepAliveNode(baseClone);
-        BlockRange().InsertBefore(call, baseClone, keepBaseAlive);
+        // If the target's backend doesn't support indirect calls with immediate operands (contained)
+        // and the method is marked as interruptible, we need to insert a GT_START_NONGC before the call.
+        // to keep the delegate object alive while we're obtaining the function pointer.
+        // Since the actual call is effectively a safe point, we don't need to insert any additional
+        // NOPs to prevent the GC starvation in single-block methods.
+        GenTree* startNonGCNode = new (comp, GT_START_NONGC) GenTree(GT_START_NONGC, TYP_VOID);
+        BlockRange().InsertBefore(newThisAddr, startNonGCNode);
     }
 #endif