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Releases: davidaknowles/leafcutter

v0.2.7

26 Sep 02:49
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v0.2.7 Pre-release
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  • prepare_results.R for leafviz received a significant re-write including
    • Removed dependence on bedtools
    • Friendlier CLI arguments
    • New documentation on the doc website
  • smart initialization got regularization (deals with co-linear covariates) and robustness to a rare divide-by-zero bug.

v0.2.6

20 Sep 21:41
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v0.2.6 Pre-release
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  • Changed PSI and deltaPSI calculations to better match empirical and be consistent across runs (issue #41)

v0.2.5

11 Sep 05:50
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v0.2.5 Pre-release
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  • Important bugfix for smart initialization when there are no technical/confounding covariates.

v0.2.4

07 Sep 19:29
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v0.2.4 Pre-release
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  • LeafViz PCA now made with ratios rather than counts
  • prepare_results now accepts covariates in support file
  • Added magrittr and stringr dependencies
  • LeafViz now allows colour and shape of points in PCA to be set to group or covariate

v0.2.3

05 Sep 22:48
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v0.2.3 Pre-release
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  • Better control of Differential splicing initialization: the default "smart" initialization is now a one-shot method of moments estimator for the null model regression coefficients, but random initialization can be optionally specified, along with the seed (see --init and --seed options of leafcutter_ds.R) (issue #33)
  • Dalila Pinto contributed a new script 'gtf2leafcutter.pl' for more robustly converting GTF files to the "annotation code" needed for leafviz. Thanks!

v0.2.2

25 Aug 20:37
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v0.2.2 Pre-release
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  • cluster_table now includes p.adjust column calculated using BH FDR control.
  • Improved gene view in LeafViz
  • check.names = F when reading counts files to avoid issues with sample file names getting changed by R
  • Removed -w option from shebang in perl scripts since this was causing issues on Linux (fine on Mac)

v0.2

04 Aug 18:39
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v0.2 Pre-release
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  • Merged covariates branch, allow for controlling for confounders.
  • Merged newstansyntax branch, reduces warnings from rstan.
  • Added leafvis shiny app.