Welcome to MTSviewer's repository, a database for the study of mitochondrial proteins which integrates AlphaFold structures, cleavage predictions, N-terminomics, and genetic variants.
- MTS predictions
- MPP cleavage sites
- Genetic variants
- Pathogenicity predictions
- N-terminomics data
- Structural visualization using AlphaFold models
All of the raw data and in-house Python scripts used in the MTSviewer build are accessible and free to download.
🔨 Please note: if you only scroll through the "Gene List", the list will be truncated alphabetically after all genes starting with S. To overcome this, you must search your gene of interest, or type the beginning letter and all of the genes will be available!
It is accessible via https://neurobioinfo.github.io/MTSvieweR
The MTSvieweR container is accessible on docker's hub. If you'd like to run it using Docker, please follow these instructions:
docker run --rm -p 3838:3838 saeidamiri1/mtsviewer:1.0.3
Any contributions or suggestions are greatly appreciated. To initiate a discussion about a new feature or a bug fix, it's typically best to open a GitHub issue. Once we reach a consensus on the way forward, you can fork the repository, make the necessary changes (using the dev branch), and then create a pull request (PR). Please ensure that PRs are targeted towards the dev branch.
If you come across a bug, kindly submit a comprehensive GitHub issue, and we'll respond promptly to address the issue.
If you use MTSviewer in your research, please consider citing our paper:
Bayne, A. N., Dong, J., Amiri, S., Farhan, S. M., & Trempe, J. F. (2023). MTSviewer: A database to visualize mitochondrial targeting sequences, cleavage sites, and mutations on protein structures. Plos one, 18(4), e0284541. https://doi.org/10.1371/journal.pone.0284541
See also our paper on PlOS ONE.
This project is licensed under the MIT License - see the LICENSE.md file for details