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Add July entry
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# Wonderful Wednesdays

**June 12th, 2024**.
**July 10th, 2024**.

The challenge for the next webinar is about platform trial designs. Details can be found [here](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-06-12).
The challenge for the next webinar is about responder definition derivation. Details can be found [here](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-07-10).

For more on PSI and wonderful wednesdays see https://www.psiweb.org/sigs-special-interest-groups/visualisation/welcome-to-wonderful-wednesdays

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We will make the submissions available to the community together with highlights of the strength and limitations through our [blog](https://vis-sig.github.io/blog/). Over time, this will lead to a gallery of visualizations for others to learn from.


## May data set
## July data set

**Upcoming July 10th, 2024 webinar**. The current data example focuses on [platform trial designs](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-06-12).
**Upcoming August 14th, 2024 webinar**. The current data example focuses on [responder definition derivation](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-07-10).

Submit your visualisations [here](https://docs.google.com/forms/d/e/1FAIpQLSdNAaiuUAD89LAdQm5KNnLWs-MjqA4pzX2VHAwN7iqwoKpi-Q/viewform) or send them to <[email protected]>!

## Next Webinar

**July 12th, 2024**.
**August 14th, 2024**.

## Previous data sets

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* [platform trial designs](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-05-08)

* [platform trial designs](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-06-12)


## Downloading single files

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# Responder definition

## Background

- When a new patient-reported outcome (PRO) is developed, there is interest in deriving the following, to support interpretation of data collected using the new tool:
- Minimal Clinically Important Difference (MCID) / Responder Definition (RD)
- Meaningful Between-Group Difference
- Meaningful Score Categories
- These are usually derived by using an existing, validated measure as the ‘gold standard’ to quantify e.g. disease status


## Data

- Simulated dataset: 1000 subjects, 2 timepoints (Baseline, Week 16)
- Treatment allocation is not important and not provided
- At each time point, data is provided for two tools:
- PGIS – the “gold standard” – graded on a 4-point scale (‘None’, ‘Mild’, ‘Moderate’, ‘Severe’)
- ‘NEWTOOL’ – the new measure, scored on an 11-point numeric rating scale from 0 to 10

## Challenge

Use visualisations to support in the derivation in any or all of the following:

- MCID
- Meaningful between-group difference
- Meaningful score categories
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- [Platform trial designs](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-05-08). Presented on **May 8th, 2024**.

- [Platform trial designs](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-06-12). Presented on **June 12th, 2024**.

- [responder definition derivation](https://github.com/VIS-SIG/Wonderful-Wednesdays/tree/master/data/2024/2024-07-10).

**NOTE** to download a single data set as a csv file, click on the raw
button and save the file. The [following link describes the process in
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