OSP-Qualification-Reports created with OSP 9.1

Open-Systems-Pharmacology · Jul 22, 2020 · 330bc74 · 330bc74
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diff --git a/...Mechanism/001_Competitive_Inhibition/001_plotDDIRatioAUCPredictedVsObserved.png b/...Mechanism/001_Competitive_Inhibition/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...Mechanism/001_Competitive_Inhibition/002_plotDDIRatioAUCResidualsVsObserved.png b/...Mechanism/001_Competitive_Inhibition/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...echanism/001_Competitive_Inhibition/003_plotDDIRatioCMAXPredictedVsObserved.png b/...echanism/001_Competitive_Inhibition/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...echanism/001_Competitive_Inhibition/004_plotDDIRatioCMAXResidualsVsObserved.png b/...echanism/001_Competitive_Inhibition/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ated_DDI/001_Mechanism/002_Induction/001_plotDDIRatioAUCPredictedVsObserved.png b/...ated_DDI/001_Mechanism/002_Induction/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ated_DDI/001_Mechanism/002_Induction/002_plotDDIRatioAUCResidualsVsObserved.png b/...ated_DDI/001_Mechanism/002_Induction/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...ted_DDI/001_Mechanism/002_Induction/003_plotDDIRatioCMAXPredictedVsObserved.png b/...ted_DDI/001_Mechanism/002_Induction/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...ted_DDI/001_Mechanism/002_Induction/004_plotDDIRatioCMAXResidualsVsObserved.png b/...ted_DDI/001_Mechanism/002_Induction/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ism/003_Mechanism_based_Inactivation/001_plotDDIRatioAUCPredictedVsObserved.png b/...ism/003_Mechanism_based_Inactivation/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ism/003_Mechanism_based_Inactivation/002_plotDDIRatioAUCResidualsVsObserved.png b/...ism/003_Mechanism_based_Inactivation/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...sm/003_Mechanism_based_Inactivation/003_plotDDIRatioCMAXPredictedVsObserved.png b/...sm/003_Mechanism_based_Inactivation/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...sm/003_Mechanism_based_Inactivation/004_plotDDIRatioCMAXResidualsVsObserved.png b/...sm/003_Mechanism_based_Inactivation/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...tion_of_Use_Case_CYP3A4-mediated_DDI/001_plotDDIRatioAUCPredictedVsObserved.png b/...tion_of_Use_Case_CYP3A4-mediated_DDI/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...I/002_Perpetrator/001_Clarithromycin/001_plotDDIRatioAUCPredictedVsObserved.png b/...I/002_Perpetrator/001_Clarithromycin/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...I/002_Perpetrator/001_Clarithromycin/002_plotDDIRatioAUCResidualsVsObserved.png b/...I/002_Perpetrator/001_Clarithromycin/002_plotDDIRatioAUCResidualsVsObserved.png
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diff --git a/.../002_Perpetrator/001_Clarithromycin/004_plotDDIRatioCMAXResidualsVsObserved.png b/.../002_Perpetrator/001_Clarithromycin/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/002_Efavirenz/001_plotDDIRatioAUCPredictedVsObserved.png b/...ed_DDI/002_Perpetrator/002_Efavirenz/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/002_Efavirenz/002_plotDDIRatioAUCResidualsVsObserved.png b/...ed_DDI/002_Perpetrator/002_Efavirenz/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/002_Efavirenz/003_plotDDIRatioCMAXPredictedVsObserved.png b/...d_DDI/002_Perpetrator/002_Efavirenz/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/002_Efavirenz/004_plotDDIRatioCMAXResidualsVsObserved.png b/...d_DDI/002_Perpetrator/002_Efavirenz/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...DDI/002_Perpetrator/003_Erythromycin/001_plotDDIRatioAUCPredictedVsObserved.png b/...DDI/002_Perpetrator/003_Erythromycin/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...DDI/002_Perpetrator/003_Erythromycin/002_plotDDIRatioAUCResidualsVsObserved.png b/...DDI/002_Perpetrator/003_Erythromycin/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...DI/002_Perpetrator/003_Erythromycin/003_plotDDIRatioCMAXPredictedVsObserved.png b/...DI/002_Perpetrator/003_Erythromycin/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...DI/002_Perpetrator/003_Erythromycin/004_plotDDIRatioCMAXResidualsVsObserved.png b/...DI/002_Perpetrator/003_Erythromycin/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/..._DDI/002_Perpetrator/004_Fluvoxamine/001_plotDDIRatioAUCPredictedVsObserved.png b/..._DDI/002_Perpetrator/004_Fluvoxamine/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/..._DDI/002_Perpetrator/004_Fluvoxamine/002_plotDDIRatioAUCResidualsVsObserved.png b/..._DDI/002_Perpetrator/004_Fluvoxamine/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...DDI/002_Perpetrator/004_Fluvoxamine/003_plotDDIRatioCMAXPredictedVsObserved.png b/...DDI/002_Perpetrator/004_Fluvoxamine/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...DDI/002_Perpetrator/004_Fluvoxamine/004_plotDDIRatioCMAXResidualsVsObserved.png b/...DDI/002_Perpetrator/004_Fluvoxamine/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...DDI/002_Perpetrator/005_Itraconazole/001_plotDDIRatioAUCPredictedVsObserved.png b/...DDI/002_Perpetrator/005_Itraconazole/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...DDI/002_Perpetrator/005_Itraconazole/002_plotDDIRatioAUCResidualsVsObserved.png b/...DDI/002_Perpetrator/005_Itraconazole/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...DI/002_Perpetrator/005_Itraconazole/003_plotDDIRatioCMAXPredictedVsObserved.png b/...DI/002_Perpetrator/005_Itraconazole/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...DI/002_Perpetrator/005_Itraconazole/004_plotDDIRatioCMAXResidualsVsObserved.png b/...DI/002_Perpetrator/005_Itraconazole/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/006_Rifampicin/001_plotDDIRatioAUCPredictedVsObserved.png b/...d_DDI/002_Perpetrator/006_Rifampicin/001_plotDDIRatioAUCPredictedVsObserved.png
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diff --git a/..._DDI/002_Perpetrator/006_Rifampicin/003_plotDDIRatioCMAXPredictedVsObserved.png b/..._DDI/002_Perpetrator/006_Rifampicin/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/..._DDI/002_Perpetrator/006_Rifampicin/004_plotDDIRatioCMAXResidualsVsObserved.png b/..._DDI/002_Perpetrator/006_Rifampicin/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/007_Verapamil/001_plotDDIRatioAUCPredictedVsObserved.png b/...ed_DDI/002_Perpetrator/007_Verapamil/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/007_Verapamil/002_plotDDIRatioAUCResidualsVsObserved.png b/...ed_DDI/002_Perpetrator/007_Verapamil/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/007_Verapamil/003_plotDDIRatioCMAXPredictedVsObserved.png b/...d_DDI/002_Perpetrator/007_Verapamil/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/007_Verapamil/004_plotDDIRatioCMAXResidualsVsObserved.png b/...d_DDI/002_Perpetrator/007_Verapamil/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...tion_of_Use_Case_CYP3A4-mediated_DDI/002_plotDDIRatioAUCResidualsVsObserved.png b/...tion_of_Use_Case_CYP3A4-mediated_DDI/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/001_Alfentanil/001_plotDDIRatioAUCPredictedVsObserved.png b/...diated_DDI/003_Victim/001_Alfentanil/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/001_Alfentanil/002_plotDDIRatioAUCResidualsVsObserved.png b/...diated_DDI/003_Victim/001_Alfentanil/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...iated_DDI/003_Victim/001_Alfentanil/003_plotDDIRatioCMAXPredictedVsObserved.png b/...iated_DDI/003_Victim/001_Alfentanil/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...iated_DDI/003_Victim/001_Alfentanil/004_plotDDIRatioCMAXResidualsVsObserved.png b/...iated_DDI/003_Victim/001_Alfentanil/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/002_Alprazolam/001_plotDDIRatioAUCPredictedVsObserved.png b/...diated_DDI/003_Victim/002_Alprazolam/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/002_Alprazolam/002_plotDDIRatioAUCResidualsVsObserved.png b/...diated_DDI/003_Victim/002_Alprazolam/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...iated_DDI/003_Victim/002_Alprazolam/003_plotDDIRatioCMAXPredictedVsObserved.png b/...iated_DDI/003_Victim/002_Alprazolam/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...iated_DDI/003_Victim/002_Alprazolam/004_plotDDIRatioCMAXResidualsVsObserved.png b/...iated_DDI/003_Victim/002_Alprazolam/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ediated_DDI/003_Victim/003_Midazolam/001_plotDDIRatioAUCPredictedVsObserved.png b/...ediated_DDI/003_Victim/003_Midazolam/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ediated_DDI/003_Victim/003_Midazolam/002_plotDDIRatioAUCResidualsVsObserved.png b/...ediated_DDI/003_Victim/003_Midazolam/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/003_Midazolam/003_plotDDIRatioCMAXPredictedVsObserved.png b/...diated_DDI/003_Victim/003_Midazolam/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/003_Midazolam/004_plotDDIRatioCMAXResidualsVsObserved.png b/...diated_DDI/003_Victim/003_Midazolam/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ediated_DDI/003_Victim/004_Triazolam/001_plotDDIRatioAUCPredictedVsObserved.png b/...ediated_DDI/003_Victim/004_Triazolam/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ediated_DDI/003_Victim/004_Triazolam/002_plotDDIRatioAUCResidualsVsObserved.png b/...ediated_DDI/003_Victim/004_Triazolam/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/004_Triazolam/003_plotDDIRatioCMAXPredictedVsObserved.png b/...diated_DDI/003_Victim/004_Triazolam/003_plotDDIRatioCMAXPredictedVsObserved.png
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diff --git a/...ion_of_Use_Case_CYP3A4-mediated_DDI/003_plotDDIRatioCMAXPredictedVsObserved.png b/...ion_of_Use_Case_CYP3A4-mediated_DDI/003_plotDDIRatioCMAXPredictedVsObserved.png
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diff --git a/...ofiles/001_3_1_Clarithromycin_-_Midazolam_DDI/001_plotComparisonTimeProfile.png b/...ofiles/001_3_1_Clarithromycin_-_Midazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...ofiles/002_3_2_Clarithromycin_-_Triazolam_DDI/001_plotComparisonTimeProfile.png b/...ofiles/002_3_2_Clarithromycin_-_Triazolam_DDI/001_plotComparisonTimeProfile.png
diff --git a/...rofiles/003_3_3_Erythromycin_-_Alfentanil_DDI/001_plotComparisonTimeProfile.png b/...rofiles/003_3_3_Erythromycin_-_Alfentanil_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...rofiles/004_3_4_Erythromycin_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png b/...rofiles/004_3_4_Erythromycin_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png
diff --git a/...Profiles/005_3_5_Erythromycin_-_Midazolam_DDI/001_plotComparisonTimeProfile.png b/...Profiles/005_3_5_Erythromycin_-_Midazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...Profiles/006_3_6_Erythromycin_-_Triazolam_DDI/001_plotComparisonTimeProfile.png b/...Profiles/006_3_6_Erythromycin_-_Triazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...Profiles/007_3_7_Fluvoxamine_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png b/...Profiles/007_3_7_Fluvoxamine_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...rofiles/009_3_9_Itraconazole_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png b/...rofiles/009_3_9_Itraconazole_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/001_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/001_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/002_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/002_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/003_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/003_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/004_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/004_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/005_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/005_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/006_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/006_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/007_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/007_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/008_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/008_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/009_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/009_plotComparisonTimeProfile.png
diff --git a/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/010_plotComparisonTimeProfile.png b/...Profiles/015_3_15_Rifampicin_-_Alfentanil_DDI/010_plotComparisonTimeProfile.png
diff --git a/...Profiles/016_3_16_Rifampicin_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png b/...Profiles/016_3_16_Rifampicin_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png
diff --git a/...Profiles/016_3_16_Rifampicin_-_Alprazolam_DDI/002_plotComparisonTimeProfile.png b/...Profiles/016_3_16_Rifampicin_-_Alprazolam_DDI/002_plotComparisonTimeProfile.png
diff --git a/...Profiles/016_3_16_Rifampicin_-_Alprazolam_DDI/003_plotComparisonTimeProfile.png b/...Profiles/016_3_16_Rifampicin_-_Alprazolam_DDI/003_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/001_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/001_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/002_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/002_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/003_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/003_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/004_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/004_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/005_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/005_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/006_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/006_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/007_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/007_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/008_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/008_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/009_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/009_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/010_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/010_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/011_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/011_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/012_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/012_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/013_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/013_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/014_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/014_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/015_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/015_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/016_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/016_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/017_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/017_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/018_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/018_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/019_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/019_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/020_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/020_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/021_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/021_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/022_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/022_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/023_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/023_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/024_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/024_plotComparisonTimeProfile.png
diff --git a/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/025_plotComparisonTimeProfile.png b/..._Profiles/017_3_17_Rifampicin_-_Midazolam_DDI/025_plotComparisonTimeProfile.png
diff --git a/..._Profiles/018_3_18_Rifampicin_-_Triazolam_DDI/001_plotComparisonTimeProfile.png b/..._Profiles/018_3_18_Rifampicin_-_Triazolam_DDI/001_plotComparisonTimeProfile.png
diff --git a/DDI_Qualification_CYP3A4/report.md b/DDI_Qualification_CYP3A4/report.md
@@ -3,10 +3,10 @@
 
 
 
-| Version                         | 1.0-OSP9.0                                                   |
+| Version                         | 1.0-OSP9.1                                                   |
 | ------------------------------- | ------------------------------------------------------------ |
 | Qualification Plan Release      | https://github.com/Open-Systems-Pharmacology/Qualification-DDI-CYP3A4/releases/tag/v1.0 |
-| OSP Version                     | 9.0                                                          |
+| OSP Version                     | 9.1                                                          |
 | Qualification Framework Version | 2.2                                                          |
 
 
@@ -531,9 +531,9 @@ In the plots,
 
 ![004_plotDDIRatioCMAXResidualsVsObserved.png](images/002_2_Qualification_of_Use_Case_CYP3A4-mediated_DDI/004_plotDDIRatioCMAXResidualsVsObserved.png)
 
-GMFE (AUC) = 1.398725 
+GMFE (AUC) = 1.398739 
 
-GMFE (CMAX) = 1.370608 
+GMFE (CMAX) = 1.370621 
 
 |AUC                       |Number|Ratio [%]|
 |-------------------------:|-----:|--------:|
@@ -557,7 +557,7 @@ GMFE (CMAX) = 1.370608
 |354   |Clarithromycin, 500 mg, PO, MD BID (4 days)                                                                                                                                                                                       |Midazolam, PO |5.871              |5.5556            |1.0568            |2.6201              |-                  |-                  |Markert 2013        |
 |1099  |Clarithromycin, 500 mg, PO, MD BID (5 days)                                                                                                                                                                                       |Midazolam, PO |7.8476             |4.84              |1.6214            |3.177               |2.69               |1.181              |Prueksaritanont 2017|
 |2030  |Clarithromycin, 500 mg, PO, MD BID (7 days)                                                                                                                                                                                       |Midazolam, PO |9.0373             |8                 |1.1297            |3.1442              |2.75               |1.1433             |Quinney 2008        |
-|2004  |Clarithromycin, 250 mg, PO, MD BID (3 days)                                                                                                                                                                                       |Midazolam, PO |1.4921             |1.9               |0.78531           |1.258               |1.75               |0.71885            |van Dyk 2018        |
+|2004  |Clarithromycin, 250 mg, PO, MD BID (3 days)                                                                                                                                                                                       |Midazolam, PO |1.4904             |1.9               |0.78442           |1.2571              |1.75               |0.71833            |van Dyk 2018        |
 |469   |Clarithromycin, 250 mg, PO, MD BID (5 days)                                                                                                                                                                                       |Midazolam, PO |2.3757             |3.5716            |0.66518           |1.5939              |2.44               |0.65325            |Yeates 1996         |
 |1102  |Clarithromycin, 500 mg, PO, MD OD (2 days)                                                                                                                                                                                        |Triazolam, PO |3.5766             |5.06              |0.70684           |2.0063              |1.968              |1.0194             |Greenblatt 1998a    |
 |779   |Erythromycin, 500 mg, PO, SD                                                                                                                                                                                                      |Alfentanil, IV|1.0294             |1.0262            |1.0031            |1                   |-                  |-                  |Bartkowski 1989     |
@@ -732,9 +732,9 @@ GMFE (CMAX) = 1.451894
 
 ![004_plotDDIRatioCMAXResidualsVsObserved.png](images/002_2_Qualification_of_Use_Case_CYP3A4-mediated_DDI/001_Mechanism/003_Mechanism_based_Inactivation/004_plotDDIRatioCMAXResidualsVsObserved.png)
 
-GMFE (AUC) = 1.271545 
+GMFE (AUC) = 1.271597 
 
-GMFE (CMAX) = 1.240603 
+GMFE (CMAX) = 1.240656 
 
 |AUC                       |Number|Ratio [%]|
 |-------------------------:|-----:|--------:|
@@ -760,9 +760,9 @@ GMFE (CMAX) = 1.240603
 
 ![004_plotDDIRatioCMAXResidualsVsObserved.png](images/002_2_Qualification_of_Use_Case_CYP3A4-mediated_DDI/002_Perpetrator/001_Clarithromycin/004_plotDDIRatioCMAXResidualsVsObserved.png)
 
-GMFE (AUC) = 1.257076 
+GMFE (AUC) = 1.257206 
 
-GMFE (CMAX) = 1.235171 
+GMFE (CMAX) = 1.235284 
 
 |AUC                       |Number|Ratio [%]|
 |-------------------------:|-----:|--------:|
@@ -996,9 +996,9 @@ GMFE (CMAX) = 1.242657
 
 ![004_plotDDIRatioCMAXResidualsVsObserved.png](images/002_2_Qualification_of_Use_Case_CYP3A4-mediated_DDI/003_Victim/003_Midazolam/004_plotDDIRatioCMAXResidualsVsObserved.png)
 
-GMFE (AUC) = 1.413926 
+GMFE (AUC) = 1.413945 
 
-GMFE (CMAX) = 1.432132 
+GMFE (CMAX) = 1.432152 
 
 |AUC                       |Number|Ratio [%]|
 |-------------------------:|-----:|--------:|

diff --git a/DDI_Qualification_CYP3A4/report.pdf b/DDI_Qualification_CYP3A4/report.pdf
diff --git a/...ication_of_Use_Case_UGT-mediated_DDI/001_plotDDIRatioAUCPredictedVsObserved.png b/...ication_of_Use_Case_UGT-mediated_DDI/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ication_of_Use_Case_UGT-mediated_DDI/002_plotDDIRatioAUCResidualsVsObserved.png b/...ication_of_Use_Case_UGT-mediated_DDI/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...cation_of_Use_Case_UGT-mediated_DDI/003_plotDDIRatioCMAXPredictedVsObserved.png b/...cation_of_Use_Case_UGT-mediated_DDI/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...cation_of_Use_Case_UGT-mediated_DDI/004_plotDDIRatioCMAXResidualsVsObserved.png b/...cation_of_Use_Case_UGT-mediated_DDI/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/001_plotComparisonTimeProfile.png b/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/001_plotComparisonTimeProfile.png
diff --git a/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/002_plotComparisonTimeProfile.png b/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/002_plotComparisonTimeProfile.png
diff --git a/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/003_plotComparisonTimeProfile.png b/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/003_plotComparisonTimeProfile.png
diff --git a/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/004_plotComparisonTimeProfile.png b/...Profiles/001_3_1_Atazanavir_-_Raltegravir_DDI/004_plotComparisonTimeProfile.png
diff --git a/...es/002_3_2_Mefenamic_acid_-_Dapagliflozin_DDI/001_plotComparisonTimeProfile.png b/...es/002_3_2_Mefenamic_acid_-_Dapagliflozin_DDI/001_plotComparisonTimeProfile.png
diff --git a/DDI_Qualification_UGT/report.md b/DDI_Qualification_UGT/report.md
@@ -3,10 +3,10 @@
 
 
 
-| Version                         | 1.1-OSP9.0                                                   |
+| Version                         | 1.1-OSP9.1                                                   |
 | ------------------------------- | ------------------------------------------------------------ |
 | Qualification Plan Release      | https://github.com/Open-Systems-Pharmacology/Qualification-DDI-UGT/releases/tag/v1.1 |
-| OSP Version                     | 9.0                                                          |
+| OSP Version                     | 9.1                                                          |
 | Qualification Framework Version | 2.2                                                          |
 
 

diff --git a/DDI_Qualification_UGT/report.pdf b/DDI_Qualification_UGT/report.pdf
diff --git a/...001_Chapter_2_1__Montelukast_PK_Ratio_tables_and_Figures/001_plotPKRatioAUC.png b/...001_Chapter_2_1__Montelukast_PK_Ratio_tables_and_Figures/001_plotPKRatioAUC.png
diff --git a/...ukast_Concentration-Time_profiles_in_Children/001_plotPopulationTimeProfile.png b/...ukast_Concentration-Time_profiles_in_Children/001_plotPopulationTimeProfile.png
diff --git a/...ukast_Concentration-Time_profiles_in_Children/002_plotPopulationTimeProfile.png b/...ukast_Concentration-Time_profiles_in_Children/002_plotPopulationTimeProfile.png
diff --git a/...mages/002_Chapter_2__Pediatric_translation_qualification/003_plotPKRatioAUC.png b/...mages/002_Chapter_2__Pediatric_translation_qualification/003_plotPKRatioAUC.png
diff --git a/...ter_3_2__Montelukast_Diagnostics_Plots/001_plotGOFMergedPredictedVsObserved.png b/...ter_3_2__Montelukast_Diagnostics_Plots/001_plotGOFMergedPredictedVsObserved.png
diff --git a/...apter_3_2__Montelukast_Diagnostics_Plots/003_plotGOFMergedResidualsOverTime.png b/...apter_3_2__Montelukast_Diagnostics_Plots/003_plotGOFMergedResidualsOverTime.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/005_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/005_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/006_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/006_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/007_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/007_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/008_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/008_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/009_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/009_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/010_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/010_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/011_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/011_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/012_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/012_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/013_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/013_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/014_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/014_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/015_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/015_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/016_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/016_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/017_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/017_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/018_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/018_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/019_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/019_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/020_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/020_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/021_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/021_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/022_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/022_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/023_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/023_plotTimeProfile.png
diff --git a/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/024_plotTimeProfile.png b/..._3_3__Montelukast_Concentration-Time_profiles_in_Adults/024_plotTimeProfile.png
diff --git a/Pediatric_Qualification_Package_CYP2C8_Ontogeny/report.md b/Pediatric_Qualification_Package_CYP2C8_Ontogeny/report.md
@@ -4,10 +4,10 @@
 
 
 
-| Version                         | 1.1-OSP9.0                                                   |
+| Version                         | 1.1-OSP9.1                                                   |
 | ------------------------------- | ------------------------------------------------------------ |
 | Qualification Plan Release      | https://github.com/Open-Systems-Pharmacology/Pediatric_Qualification_Package_CYP2C8_Ontogeny/releases/tag/v1.1 |
-| OSP Version                     | 9.0                                                          |
+| OSP Version                     | 9.1                                                          |
 | Qualification Framework Version | 2.2                                                          |
 
 

diff --git a/Pediatric_Qualification_Package_CYP2C8_Ontogeny/report.pdf b/Pediatric_Qualification_Package_CYP2C8_Ontogeny/report.pdf
diff --git a/..._Pediatric_Translation_and_CYP3A4_Ontogeny_Qualification/001_plotPKRatioAUC.png b/..._Pediatric_Translation_and_CYP3A4_Ontogeny_Qualification/001_plotPKRatioAUC.png
diff --git a/.../001_Chapter_2_1__Sufentanil_PK_Ratio_tables_and_Figures/001_plotPKRatioAUC.png b/.../001_Chapter_2_1__Sufentanil_PK_Ratio_tables_and_Figures/001_plotPKRatioAUC.png
diff --git a/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/001_plotTimeProfile.png b/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/001_plotTimeProfile.png
diff --git a/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/002_plotTimeProfile.png b/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/002_plotTimeProfile.png
diff --git a/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/003_plotTimeProfile.png b/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/003_plotTimeProfile.png
diff --git a/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/004_plotTimeProfile.png b/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/004_plotTimeProfile.png
diff --git a/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/005_plotTimeProfile.png b/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/005_plotTimeProfile.png
diff --git a/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/006_plotTimeProfile.png b/...2_2__Sufentanil_Concentration-Time_profiles_in_Children/006_plotTimeProfile.png
diff --git a/.../003_Chapter_2_3__Alfentanil_PK_Ratio_tables_and_Figures/001_plotPKRatioAUC.png b/.../003_Chapter_2_3__Alfentanil_PK_Ratio_tables_and_Figures/001_plotPKRatioAUC.png
diff --git a/...2_4__Alfentanil_Concentration-Time_profiles_in_Children/001_plotTimeProfile.png b/...2_4__Alfentanil_Concentration-Time_profiles_in_Children/001_plotTimeProfile.png
diff --git a/...2_4__Alfentanil_Concentration-Time_profiles_in_Children/002_plotTimeProfile.png b/...2_4__Alfentanil_Concentration-Time_profiles_in_Children/002_plotTimeProfile.png
diff --git a/...tanil_Concentration-Time_profiles_in_Children/003_plotPopulationTimeProfile.png b/...tanil_Concentration-Time_profiles_in_Children/003_plotPopulationTimeProfile.png
diff --git a/...tanil_Concentration-Time_profiles_in_Children/004_plotPopulationTimeProfile.png b/...tanil_Concentration-Time_profiles_in_Children/004_plotPopulationTimeProfile.png
diff --git a/...2_Chapter_2__Pediatric_translation_qualification_results/005_plotPKRatioAUC.png b/...2_Chapter_2__Pediatric_translation_qualification_results/005_plotPKRatioAUC.png
diff --git a/...pter_3_2__Sufentanil_Diagnostics_Plots/001_plotGOFMergedPredictedVsObserved.png b/...pter_3_2__Sufentanil_Diagnostics_Plots/001_plotGOFMergedPredictedVsObserved.png
diff --git a/...hapter_3_2__Sufentanil_Diagnostics_Plots/003_plotGOFMergedResidualsOverTime.png b/...hapter_3_2__Sufentanil_Diagnostics_Plots/003_plotGOFMergedResidualsOverTime.png
diff --git a/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png b/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png
diff --git a/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png b/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png
diff --git a/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png b/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png
diff --git a/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png b/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png
diff --git a/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/005_plotTimeProfile.png b/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/005_plotTimeProfile.png
diff --git a/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/006_plotTimeProfile.png b/...r_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/006_plotTimeProfile.png
diff --git a/Pediatric_Qualification_Package_CYP3A4_Ontogeny/report.md b/Pediatric_Qualification_Package_CYP3A4_Ontogeny/report.md
@@ -4,10 +4,10 @@
 
 
 
-| Version                         | 1.1-OSP9.0                                                   |
+| Version                         | 1.2-OSP9.1                                                   |
 | ------------------------------- | ------------------------------------------------------------ |
-| Qualification Plan Release      | https://github.com/Open-Systems-Pharmacology/Pediatric_Qualification_Package_CYP3A4_Ontogeny/releases/tag/v1.1 |
-| OSP Version                     | 9.0                                                          |
+| Qualification Plan Release      | https://github.com/Open-Systems-Pharmacology/Pediatric_Qualification_Package_CYP3A4_Ontogeny/releases/tag/v1.2 |
+| OSP Version                     | 9.1                                                          |
 | Qualification Framework Version | 2.2                                                          |
 
 
@@ -73,7 +73,6 @@ To qualify the OSP suite for the pediatric translation of the pharmacokinetics o
 [4] [Alfentanil-Model, Whole-body PBPK model of Alfentanil. https://github.com/Open-Systems-Pharmacology/Alfentanil-Model](https://github.com/incei/Alfentanil-Model)
 
 [5] [Sufentanil-Model, Whole-body PBPK model of Sufentanil. https://github.com/Open-Systems-Pharmacology/Sufentanil-Model](https://github.com/incei/Sufentanil-Model)
-
 # Chapter 2: Pediatric translation qualification results
 ## Evaluation of Pediatric translation
 
@@ -90,8 +89,7 @@ The ratios of predicted over observed mean AUC or CL values from all compound we
 In the next sections the demographics as well as the evaluation results of the predictive performance of the specific compound PBPK models in children can be found.  
 
 
-
-![001_plotPKRatioAUC.png](images/001_Chapter_1__Introduction_to_Pediatric_Translation_and_CYP3A4_Ontogeny_Qualification/001_plotPKRatioAUC.png)
+![005_plotPKRatioAUC.png](images/002_Chapter_2__Pediatric_translation_qualification_results/005_plotPKRatioAUC.png)
 
 GMFE (AUC) = 1.254230 
 
@@ -323,10 +321,30 @@ Intrinsic clearance | 9.6138746106 l/min | Parameter Identification-Parameter Id
 Below you find the input goodness-of-fit visual diagnostic plots for sufentanil PBPK model performance (observed versus individually simulated plasma concentration and weighted residuals versus time) of all adult data.
 
 
+![001_plotGOFMergedPredictedVsObserved.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/002_Chapter_3_2__Sufentanil_Diagnostics_Plots/001_plotGOFMergedPredictedVsObserved.png)
+
+GMFE = 1.402222 
+
+![003_plotGOFMergedResidualsOverTime.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/002_Chapter_3_2__Sufentanil_Diagnostics_Plots/003_plotGOFMergedResidualsOverTime.png)
+
+GMFE = 1.402222 
+
 ## Chapter 3.3: Sufentanil Concentration-Time profiles in Adults
 #### Concentration-Time Profiles
 
 Simulated versus observed plasma concentration-time profiles of all data are listed below.
+![001_plotTimeProfile.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/003_Chapter_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png)
+
+![002_plotTimeProfile.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/003_Chapter_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png)
+
+![003_plotTimeProfile.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/003_Chapter_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png)
+
+![004_plotTimeProfile.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/003_Chapter_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png)
+
+![005_plotTimeProfile.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/003_Chapter_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/005_plotTimeProfile.png)
+
+![006_plotTimeProfile.png](images/003_Chapter_3__Adult_PBPK_model_building_and_performance/003_Chapter_3_3__Sufentanil_Concentration-Time_profiles_in_Adults/006_plotTimeProfile.png)
+
 ## Chapter 3.4: Alfentanil Input Tables
 ### Alfentanil model
 

diff --git a/Pediatric_Qualification_Package_CYP3A4_Ontogeny/report.pdf b/Pediatric_Qualification_Package_CYP3A4_Ontogeny/report.pdf
diff --git a/...ion/001_Chapter_2_1__Amikacin_PK_Ratio_tables_and_Figures/001_plotPKRatioCL.png b/...ion/001_Chapter_2_1__Amikacin_PK_Ratio_tables_and_Figures/001_plotPKRatioCL.png
diff --git a/...n/003_Chapter_2_3__Vancomycin_PK_Ratio_tables_and_Figures/001_plotPKRatioCL.png b/...n/003_Chapter_2_3__Vancomycin_PK_Ratio_tables_and_Figures/001_plotPKRatioCL.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/001_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/001_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/002_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/002_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/003_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/003_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/004_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/004_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/005_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/005_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/006_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/006_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/007_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/007_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/008_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/008_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/009_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/009_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/010_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/010_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/011_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/011_plotPopulationTimeProfile.png
diff --git a/...mycin_Concentration-Time_profiles_in_Children/012_plotPopulationTimeProfile.png b/...mycin_Concentration-Time_profiles_in_Children/012_plotPopulationTimeProfile.png
diff --git a/...images/002_Chapter_2__Pediatric_translation_qualification/005_plotPKRatioCL.png b/...images/002_Chapter_2__Pediatric_translation_qualification/005_plotPKRatioCL.png
diff --git a/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png b/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png
diff --git a/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png b/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png
diff --git a/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png b/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png
diff --git a/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png b/...ter_3_2__Amikacin_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png
diff --git a/...mikacin_Concentration-Time_profiles_in_Adults/005_plotPopulationTimeProfile.png b/...mikacin_Concentration-Time_profiles_in_Adults/005_plotPopulationTimeProfile.png
diff --git a/...mikacin_Concentration-Time_profiles_in_Adults/006_plotPopulationTimeProfile.png b/...mikacin_Concentration-Time_profiles_in_Adults/006_plotPopulationTimeProfile.png
diff --git a/...pter_3_4__Vancomycin_Diagnostics_Plots/001_plotGOFMergedPredictedVsObserved.png b/...pter_3_4__Vancomycin_Diagnostics_Plots/001_plotGOFMergedPredictedVsObserved.png
diff --git a/...hapter_3_4__Vancomycin_Diagnostics_Plots/003_plotGOFMergedResidualsOverTime.png b/...hapter_3_4__Vancomycin_Diagnostics_Plots/003_plotGOFMergedResidualsOverTime.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/001_plotTimeProfile.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/002_plotTimeProfile.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/003_plotTimeProfile.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/004_plotTimeProfile.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/005_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/005_plotTimeProfile.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/006_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/006_plotTimeProfile.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/007_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/007_plotTimeProfile.png
diff --git a/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/008_plotTimeProfile.png b/...r_3_5__Vancomycin_Concentration-Time_profiles_in_Adults/008_plotTimeProfile.png
diff --git a/Pediatric_Qualification_Package_GFR_Ontogeny/report.md b/Pediatric_Qualification_Package_GFR_Ontogeny/report.md
@@ -3,10 +3,10 @@
 
 
 
-| Version                         | 1.1-OSP9.0                                                   |
+| Version                         | 1.1-OSP9.1                                                   |
 | ------------------------------- | ------------------------------------------------------------ |
 | Qualification Plan Release      | https://github.com/Open-Systems-Pharmacology/Pediatric_Qualification_Package_GFR_Ontogeny/releases/tag/v1.1 |
-| OSP Version                     | 9.0                                                          |
+| OSP Version                     | 9.1                                                          |
 | Qualification Framework Version | 2.2                                                          |
 
 

diff --git a/Pediatric_Qualification_Package_GFR_Ontogeny/report.pdf b/Pediatric_Qualification_Package_GFR_Ontogeny/report.pdf