DDI-CYP3A4 Report 1.5

Open-Systems-Pharmacology · Feb 11, 2024 · 04fc843 · 04fc843
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diff --git a/...ated_DDI/001_Mechanism/001_Induction/001_plotDDIRatioAUCPredictedVsObserved.png b/...ated_DDI/001_Mechanism/001_Induction/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ated_DDI/001_Mechanism/001_Induction/002_plotDDIRatioAUCResidualsVsObserved.png b/...ated_DDI/001_Mechanism/001_Induction/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...ted_DDI/001_Mechanism/001_Induction/003_plotDDIRatioCMAXPredictedVsObserved.png b/...ted_DDI/001_Mechanism/001_Induction/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...ted_DDI/001_Mechanism/001_Induction/004_plotDDIRatioCMAXResidualsVsObserved.png b/...ted_DDI/001_Mechanism/001_Induction/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ism/002_Mechanism_based_Inactivation/001_plotDDIRatioAUCPredictedVsObserved.png b/...ism/002_Mechanism_based_Inactivation/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ism/002_Mechanism_based_Inactivation/002_plotDDIRatioAUCResidualsVsObserved.png b/...ism/002_Mechanism_based_Inactivation/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...sm/002_Mechanism_based_Inactivation/003_plotDDIRatioCMAXPredictedVsObserved.png b/...sm/002_Mechanism_based_Inactivation/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...sm/002_Mechanism_based_Inactivation/004_plotDDIRatioCMAXResidualsVsObserved.png b/...sm/002_Mechanism_based_Inactivation/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/..._Mechanism/003_Reversible_Inhibition/001_plotDDIRatioAUCPredictedVsObserved.png b/..._Mechanism/003_Reversible_Inhibition/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/..._Mechanism/003_Reversible_Inhibition/002_plotDDIRatioAUCResidualsVsObserved.png b/..._Mechanism/003_Reversible_Inhibition/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...Mechanism/003_Reversible_Inhibition/003_plotDDIRatioCMAXPredictedVsObserved.png b/...Mechanism/003_Reversible_Inhibition/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...Mechanism/003_Reversible_Inhibition/004_plotDDIRatioCMAXResidualsVsObserved.png b/...Mechanism/003_Reversible_Inhibition/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...tion_of_Use_Case_CYP3A4-mediated_DDI/001_plotDDIRatioAUCPredictedVsObserved.png b/...tion_of_Use_Case_CYP3A4-mediated_DDI/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...DI/002_Perpetrator/001_Carbamazepine/001_plotDDIRatioAUCPredictedVsObserved.png b/...DI/002_Perpetrator/001_Carbamazepine/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...DI/002_Perpetrator/001_Carbamazepine/002_plotDDIRatioAUCResidualsVsObserved.png b/...DI/002_Perpetrator/001_Carbamazepine/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...I/002_Perpetrator/001_Carbamazepine/003_plotDDIRatioCMAXPredictedVsObserved.png b/...I/002_Perpetrator/001_Carbamazepine/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...I/002_Perpetrator/001_Carbamazepine/004_plotDDIRatioCMAXResidualsVsObserved.png b/...I/002_Perpetrator/001_Carbamazepine/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/002_Cimetidine/001_plotDDIRatioAUCPredictedVsObserved.png b/...d_DDI/002_Perpetrator/002_Cimetidine/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/002_Cimetidine/002_plotDDIRatioAUCResidualsVsObserved.png b/...d_DDI/002_Perpetrator/002_Cimetidine/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/..._DDI/002_Perpetrator/002_Cimetidine/003_plotDDIRatioCMAXPredictedVsObserved.png b/..._DDI/002_Perpetrator/002_Cimetidine/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/..._DDI/002_Perpetrator/002_Cimetidine/004_plotDDIRatioCMAXResidualsVsObserved.png b/..._DDI/002_Perpetrator/002_Cimetidine/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...I/002_Perpetrator/003_Clarithromycin/001_plotDDIRatioAUCPredictedVsObserved.png b/...I/002_Perpetrator/003_Clarithromycin/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...I/002_Perpetrator/003_Clarithromycin/002_plotDDIRatioAUCResidualsVsObserved.png b/...I/002_Perpetrator/003_Clarithromycin/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/.../002_Perpetrator/003_Clarithromycin/003_plotDDIRatioCMAXPredictedVsObserved.png b/.../002_Perpetrator/003_Clarithromycin/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/.../002_Perpetrator/003_Clarithromycin/004_plotDDIRatioCMAXResidualsVsObserved.png b/.../002_Perpetrator/003_Clarithromycin/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/004_Efavirenz/001_plotDDIRatioAUCPredictedVsObserved.png b/...ed_DDI/002_Perpetrator/004_Efavirenz/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/004_Efavirenz/002_plotDDIRatioAUCResidualsVsObserved.png b/...ed_DDI/002_Perpetrator/004_Efavirenz/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/004_Efavirenz/003_plotDDIRatioCMAXPredictedVsObserved.png b/...d_DDI/002_Perpetrator/004_Efavirenz/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/004_Efavirenz/004_plotDDIRatioCMAXResidualsVsObserved.png b/...d_DDI/002_Perpetrator/004_Efavirenz/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...DDI/002_Perpetrator/005_Erythromycin/001_plotDDIRatioAUCPredictedVsObserved.png b/...DDI/002_Perpetrator/005_Erythromycin/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...DDI/002_Perpetrator/005_Erythromycin/002_plotDDIRatioAUCResidualsVsObserved.png b/...DDI/002_Perpetrator/005_Erythromycin/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...DI/002_Perpetrator/005_Erythromycin/003_plotDDIRatioCMAXPredictedVsObserved.png b/...DI/002_Perpetrator/005_Erythromycin/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...DI/002_Perpetrator/005_Erythromycin/004_plotDDIRatioCMAXResidualsVsObserved.png b/...DI/002_Perpetrator/005_Erythromycin/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/..._DDI/002_Perpetrator/006_Fluconazole/001_plotDDIRatioAUCPredictedVsObserved.png b/..._DDI/002_Perpetrator/006_Fluconazole/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/..._DDI/002_Perpetrator/006_Fluconazole/002_plotDDIRatioAUCResidualsVsObserved.png b/..._DDI/002_Perpetrator/006_Fluconazole/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...DDI/002_Perpetrator/006_Fluconazole/003_plotDDIRatioCMAXPredictedVsObserved.png b/...DDI/002_Perpetrator/006_Fluconazole/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...DDI/002_Perpetrator/006_Fluconazole/004_plotDDIRatioCMAXResidualsVsObserved.png b/...DDI/002_Perpetrator/006_Fluconazole/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/..._DDI/002_Perpetrator/007_Fluvoxamine/001_plotDDIRatioAUCPredictedVsObserved.png b/..._DDI/002_Perpetrator/007_Fluvoxamine/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/..._DDI/002_Perpetrator/007_Fluvoxamine/002_plotDDIRatioAUCResidualsVsObserved.png b/..._DDI/002_Perpetrator/007_Fluvoxamine/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...DDI/002_Perpetrator/007_Fluvoxamine/003_plotDDIRatioCMAXPredictedVsObserved.png b/...DDI/002_Perpetrator/007_Fluvoxamine/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...DDI/002_Perpetrator/007_Fluvoxamine/004_plotDDIRatioCMAXResidualsVsObserved.png b/...DDI/002_Perpetrator/007_Fluvoxamine/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...DDI/002_Perpetrator/008_Itraconazole/001_plotDDIRatioAUCPredictedVsObserved.png b/...DDI/002_Perpetrator/008_Itraconazole/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...DDI/002_Perpetrator/008_Itraconazole/002_plotDDIRatioAUCResidualsVsObserved.png b/...DDI/002_Perpetrator/008_Itraconazole/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...DI/002_Perpetrator/008_Itraconazole/003_plotDDIRatioCMAXPredictedVsObserved.png b/...DI/002_Perpetrator/008_Itraconazole/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...DI/002_Perpetrator/008_Itraconazole/004_plotDDIRatioCMAXResidualsVsObserved.png b/...DI/002_Perpetrator/008_Itraconazole/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/009_Rifampicin/001_plotDDIRatioAUCPredictedVsObserved.png b/...d_DDI/002_Perpetrator/009_Rifampicin/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/009_Rifampicin/002_plotDDIRatioAUCResidualsVsObserved.png b/...d_DDI/002_Perpetrator/009_Rifampicin/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/..._DDI/002_Perpetrator/009_Rifampicin/003_plotDDIRatioCMAXPredictedVsObserved.png b/..._DDI/002_Perpetrator/009_Rifampicin/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/..._DDI/002_Perpetrator/009_Rifampicin/004_plotDDIRatioCMAXResidualsVsObserved.png b/..._DDI/002_Perpetrator/009_Rifampicin/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/010_Verapamil/001_plotDDIRatioAUCPredictedVsObserved.png b/...ed_DDI/002_Perpetrator/010_Verapamil/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ed_DDI/002_Perpetrator/010_Verapamil/002_plotDDIRatioAUCResidualsVsObserved.png b/...ed_DDI/002_Perpetrator/010_Verapamil/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/010_Verapamil/003_plotDDIRatioCMAXPredictedVsObserved.png b/...d_DDI/002_Perpetrator/010_Verapamil/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...d_DDI/002_Perpetrator/010_Verapamil/004_plotDDIRatioCMAXResidualsVsObserved.png b/...d_DDI/002_Perpetrator/010_Verapamil/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...tion_of_Use_Case_CYP3A4-mediated_DDI/002_plotDDIRatioAUCResidualsVsObserved.png b/...tion_of_Use_Case_CYP3A4-mediated_DDI/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/001_Alfentanil/001_plotDDIRatioAUCPredictedVsObserved.png b/...diated_DDI/003_Victim/001_Alfentanil/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/001_Alfentanil/002_plotDDIRatioAUCResidualsVsObserved.png b/...diated_DDI/003_Victim/001_Alfentanil/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...iated_DDI/003_Victim/001_Alfentanil/003_plotDDIRatioCMAXPredictedVsObserved.png b/...iated_DDI/003_Victim/001_Alfentanil/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...iated_DDI/003_Victim/001_Alfentanil/004_plotDDIRatioCMAXResidualsVsObserved.png b/...iated_DDI/003_Victim/001_Alfentanil/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/002_Alprazolam/001_plotDDIRatioAUCPredictedVsObserved.png b/...diated_DDI/003_Victim/002_Alprazolam/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/002_Alprazolam/002_plotDDIRatioAUCResidualsVsObserved.png b/...diated_DDI/003_Victim/002_Alprazolam/002_plotDDIRatioAUCResidualsVsObserved.png
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diff --git a/...ted_DDI/003_Victim/003_Carbamazepine/001_plotDDIRatioAUCPredictedVsObserved.png b/...ted_DDI/003_Victim/003_Carbamazepine/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ted_DDI/003_Victim/003_Carbamazepine/002_plotDDIRatioAUCResidualsVsObserved.png b/...ted_DDI/003_Victim/003_Carbamazepine/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...ed_DDI/003_Victim/003_Carbamazepine/003_plotDDIRatioCMAXPredictedVsObserved.png b/...ed_DDI/003_Victim/003_Carbamazepine/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...ed_DDI/003_Victim/003_Carbamazepine/004_plotDDIRatioCMAXResidualsVsObserved.png b/...ed_DDI/003_Victim/003_Carbamazepine/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ediated_DDI/003_Victim/004_Efavirenz/001_plotDDIRatioAUCPredictedVsObserved.png b/...ediated_DDI/003_Victim/004_Efavirenz/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ediated_DDI/003_Victim/004_Efavirenz/002_plotDDIRatioAUCResidualsVsObserved.png b/...ediated_DDI/003_Victim/004_Efavirenz/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/004_Efavirenz/003_plotDDIRatioCMAXPredictedVsObserved.png b/...diated_DDI/003_Victim/004_Efavirenz/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/004_Efavirenz/004_plotDDIRatioCMAXResidualsVsObserved.png b/...diated_DDI/003_Victim/004_Efavirenz/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ediated_DDI/003_Victim/005_Midazolam/001_plotDDIRatioAUCPredictedVsObserved.png b/...ediated_DDI/003_Victim/005_Midazolam/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ediated_DDI/003_Victim/005_Midazolam/002_plotDDIRatioAUCResidualsVsObserved.png b/...ediated_DDI/003_Victim/005_Midazolam/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/005_Midazolam/003_plotDDIRatioCMAXPredictedVsObserved.png b/...diated_DDI/003_Victim/005_Midazolam/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/005_Midazolam/004_plotDDIRatioCMAXResidualsVsObserved.png b/...diated_DDI/003_Victim/005_Midazolam/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ediated_DDI/003_Victim/006_Triazolam/001_plotDDIRatioAUCPredictedVsObserved.png b/...ediated_DDI/003_Victim/006_Triazolam/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ediated_DDI/003_Victim/006_Triazolam/002_plotDDIRatioAUCResidualsVsObserved.png b/...ediated_DDI/003_Victim/006_Triazolam/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/006_Triazolam/003_plotDDIRatioCMAXPredictedVsObserved.png b/...diated_DDI/003_Victim/006_Triazolam/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/006_Triazolam/004_plotDDIRatioCMAXResidualsVsObserved.png b/...diated_DDI/003_Victim/006_Triazolam/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ediated_DDI/003_Victim/007_Verapamil/001_plotDDIRatioAUCPredictedVsObserved.png b/...ediated_DDI/003_Victim/007_Verapamil/001_plotDDIRatioAUCPredictedVsObserved.png
diff --git a/...ediated_DDI/003_Victim/007_Verapamil/002_plotDDIRatioAUCResidualsVsObserved.png b/...ediated_DDI/003_Victim/007_Verapamil/002_plotDDIRatioAUCResidualsVsObserved.png
diff --git a/...diated_DDI/003_Victim/007_Verapamil/003_plotDDIRatioCMAXPredictedVsObserved.png b/...diated_DDI/003_Victim/007_Verapamil/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...diated_DDI/003_Victim/007_Verapamil/004_plotDDIRatioCMAXResidualsVsObserved.png b/...diated_DDI/003_Victim/007_Verapamil/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ion_of_Use_Case_CYP3A4-mediated_DDI/003_plotDDIRatioCMAXPredictedVsObserved.png b/...ion_of_Use_Case_CYP3A4-mediated_DDI/003_plotDDIRatioCMAXPredictedVsObserved.png
diff --git a/...ion_of_Use_Case_CYP3A4-mediated_DDI/004_plotDDIRatioCMAXResidualsVsObserved.png b/...ion_of_Use_Case_CYP3A4-mediated_DDI/004_plotDDIRatioCMAXResidualsVsObserved.png
diff --git a/...ofiles/001_3_1_Carbamazepine_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png b/...ofiles/001_3_1_Carbamazepine_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png
diff --git a/...rofiles/002_3_2_Carbamazepine_-_Efavirenz_DDI/001_plotComparisonTimeProfile.png b/...rofiles/002_3_2_Carbamazepine_-_Efavirenz_DDI/001_plotComparisonTimeProfile.png
diff --git a/...rofiles/003_3_3_Carbamazepine_-_Midazolam_DDI/001_plotComparisonTimeProfile.png b/...rofiles/003_3_3_Carbamazepine_-_Midazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...rofiles/003_3_3_Carbamazepine_-_Midazolam_DDI/003_plotComparisonTimeProfile.png b/...rofiles/003_3_3_Carbamazepine_-_Midazolam_DDI/003_plotComparisonTimeProfile.png
diff --git a/..._Profiles/004_3_4_Cimetidine_-_Alfentanil_DDI/001_plotComparisonTimeProfile.png b/..._Profiles/004_3_4_Cimetidine_-_Alfentanil_DDI/001_plotComparisonTimeProfile.png
diff --git a/..._Profiles/005_3_5_Cimetidine_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png b/..._Profiles/005_3_5_Cimetidine_-_Alprazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...e_Profiles/007_3_7_Cimetidine_-_Midazolam_DDI/001_plotComparisonTimeProfile.png b/...e_Profiles/007_3_7_Cimetidine_-_Midazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...e_Profiles/007_3_7_Cimetidine_-_Midazolam_DDI/006_plotComparisonTimeProfile.png b/...e_Profiles/007_3_7_Cimetidine_-_Midazolam_DDI/006_plotComparisonTimeProfile.png
diff --git a/...e_Profiles/008_3_8_Cimetidine_-_Triazolam_DDI/001_plotComparisonTimeProfile.png b/...e_Profiles/008_3_8_Cimetidine_-_Triazolam_DDI/001_plotComparisonTimeProfile.png
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diff --git a/...e_Profiles/009_3_9_Cimetidine_-_Verapamil_DDI/001_plotComparisonTimeProfile.png b/...e_Profiles/009_3_9_Cimetidine_-_Verapamil_DDI/001_plotComparisonTimeProfile.png
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