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Infers a topology of relationships between different datasets, such as multi-omics and phenotypic data recorded on the same samples.

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iTOP

iTOP is the R package accompanying our publication on the inference of topologies of relationships between datasets, such as multi-omics and phenotypic data recorded on the same samples (Aben et al., 2018, doi.org/10.1101/293993). We based this methodology on the RV coefficient, a measure of matrix correlation, which we have extended for partial matrix correlations and binary data.

The R package is available on CRAN. It can be installed within R using:

install.packages("iTOP")

A quick start can be found here. The reference manual can be found here.

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Infers a topology of relationships between different datasets, such as multi-omics and phenotypic data recorded on the same samples.

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