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JEFworks authored Jan 30, 2024
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# Spatial Experiments raster (SEraster)

`SEraster` is a pre-processing tool to enable scalable and accurate analysis of large-scale spatial omics datasets with existing tools.
`SEraster` is a rasterization preprocessing framework that aggregates cellular information into spatial pixels to enhance the scalability of spatial omics data analysis.

<p align="center">
<img src="https://github.com/JEFworks/SEraster/blob/main/docs/images/seraster_logo_hex.png?raw=true" height="200"/>
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<img src="https://github.com/JEFworks/SEraster/blob/main/docs/images/rasterized_ct_inhibitory.png?raw=true" height="400"/>
</p>

### Downstream Analysis
### Sample Downstream Analysis

We will highlight spatial variable gene (SVG) and cell-type cooccurrence analyses as examples of downstream analysis that benefit from SEraster.
`SEraster` returns rasteriezd gene-expression and cell-type information as `SpatialExperiment` objects that can be integrated with other existing downstream analysis tools. We demonstrate below spatial variable gene (SVG) and cell-type cooccurrence analyses as examples of such potential downstream analysis.

#### Spatial variable gene (SVG) analysis

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