notebooks/Regression_MLP.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Import all the necessary packages as well as the module to perform Patch2Self"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "import sys\n",
    "sys.path.append(\"..\")\n",
    "\n",
    "import numpy as np\n",
    "import time\n",
    "import matplotlib.pyplot as plt\n",
    "from model.patch2self import patch2self\n",
    "from dipy.io.image import save_nifti, load_nifti\n",
    "from dipy.data import read_stanford_labels"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### To showcase the denoising from Patch2Self we will make use of the Stanford HARDI dataset available as a part of DIPY [https://dipy.org]. The 'get_data()' utility is the fetcher that automatically downloads the dataset and loads the Nifti file as follows:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    }
   ],
   "source": [
    "hardi_img, gtab, labels_img = read_stanford_labels()\n",
    "data = hardi_img.get_data()\n",
    "affine = np.eye(4)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### Patch2Self via Multi-layer Perceptron"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "(160, 1, 652536)\n",
      "Patch Extraction Done...\n",
      "Training with patch-radius:  [0 0 0]\n"
     ]
    },
    {
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     "output_type": "stream",
     "text": []
    },
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    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  74\n",
      "Denoising Volume  74  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  75\n",
      "Denoising Volume  75  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  76\n",
      "Denoising Volume  76  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  77\n",
      "Denoising Volume  77  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  78\n",
      "Denoising Volume  78  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  79\n",
      "Denoising Volume  79  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  80\n",
      "Denoising Volume  80  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  81\n",
      "Denoising Volume  81  Complete...\n",
      " -> Trained to Denoise Volume:  82\n",
      "Denoising Volume  82  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  83\n",
      "Denoising Volume  83  Complete...\n",
      " -> Trained to Denoise Volume:  84\n",
      "Denoising Volume  84  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  85\n",
      "Denoising Volume  85  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  86\n",
      "Denoising Volume  86  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  87\n",
      "Denoising Volume  87  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  88\n",
      "Denoising Volume  88  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  89\n",
      "Denoising Volume  89  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  90\n",
      "Denoising Volume  90  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  91\n",
      "Denoising Volume  91  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  92\n",
      "Denoising Volume  92  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  93\n",
      "Denoising Volume  93  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  94\n",
      "Denoising Volume  94  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  95\n",
      "Denoising Volume  95  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  96\n",
      "Denoising Volume  96  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  97\n",
      "Denoising Volume  97  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  98\n",
      "Denoising Volume  98  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  99\n",
      "Denoising Volume  99  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  100\n",
      "Denoising Volume  100  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  101\n",
      "Denoising Volume  101  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  102\n",
      "Denoising Volume  102  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  103\n",
      "Denoising Volume  103  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  104\n",
      "Denoising Volume  104  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  105\n",
      "Denoising Volume  105  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  106\n",
      "Denoising Volume  106  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  107\n",
      "Denoising Volume  107  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  108\n",
      "Denoising Volume  108  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  109\n",
      "Denoising Volume  109  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  110\n",
      "Denoising Volume  110  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  111\n",
      "Denoising Volume  111  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  112\n",
      "Denoising Volume  112  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  113\n",
      "Denoising Volume  113  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  114\n",
      "Denoising Volume  114  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  115\n",
      "Denoising Volume  115  Complete...\n",
      " -> Trained to Denoise Volume:  116\n",
      "Denoising Volume  116  Complete...\n",
      " -> Trained to Denoise Volume:  117\n",
      "Denoising Volume  117  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  118\n",
      "Denoising Volume  118  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  119\n",
      "Denoising Volume  119  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  120\n",
      "Denoising Volume  120  Complete...\n",
      " -> Trained to Denoise Volume:  121\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Denoising Volume  121  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  122\n",
      "Denoising Volume  122  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  123\n",
      "Denoising Volume  123  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  124\n",
      "Denoising Volume  124  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  125\n",
      "Denoising Volume  125  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  126\n",
      "Denoising Volume  126  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  127\n",
      "Denoising Volume  127  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  128\n",
      "Denoising Volume  128  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  129\n",
      "Denoising Volume  129  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  130\n",
      "Denoising Volume  130  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  131\n",
      "Denoising Volume  131  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  132\n",
      "Denoising Volume  132  Complete...\n",
      " -> Trained to Denoise Volume:  133\n",
      "Denoising Volume  133  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  134\n",
      "Denoising Volume  134  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  135\n",
      "Denoising Volume  135  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  136\n",
      "Denoising Volume  136  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  137\n",
      "Denoising Volume  137  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  138\n",
      "Denoising Volume  138  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  139\n",
      "Denoising Volume  139  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  140\n",
      "Denoising Volume  140  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  141\n",
      "Denoising Volume  141  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  142\n",
      "Denoising Volume  142  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  143\n",
      "Denoising Volume  143  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  144\n",
      "Denoising Volume  144  Complete...\n",
      " -> Trained to Denoise Volume:  145\n",
      "Denoising Volume  145  Complete...\n",
      " -> Trained to Denoise Volume:  146\n",
      "Denoising Volume  146  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  147\n",
      "Denoising Volume  147  Complete...\n",
      " -> Trained to Denoise Volume:  148\n",
      "Denoising Volume  148  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  149\n",
      "Denoising Volume  149  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  150\n",
      "Denoising Volume  150  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  151\n",
      "Denoising Volume  151  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  152\n",
      "Denoising Volume  152  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  153\n",
      "Denoising Volume  153  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  154\n",
      "Denoising Volume  154  Complete...\n",
      " -> Trained to Denoise Volume:  155\n",
      "Denoising Volume  155  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  156\n",
      "Denoising Volume  156  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  157\n",
      "Denoising Volume  157  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  158\n",
      "Denoising Volume  158  Complete...\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": []
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      " -> Trained to Denoise Volume:  159\n",
      "Denoising Volume  159  Complete...\n",
      "Time Taken:  31609.0245513916\n"
     ]
    }
   ],
   "source": [
    "t1 = time.time()\n",
    "denoised_sh_mlp = patch2self(data, model='mlp')\n",
    "t2 = time.time()\n",
    "print('Time Taken: ', t2-t1)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "- #### Next we will visualize the output of the denoising and plot the residuals using sum of squared differences\n",
    "- #### We show the output for slice 35 and volume 127"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {
    "scrolled": false
   },
   "outputs": [
    {
     "data": {
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      "text/plain": [
       "<Figure size 2160x2160 with 3 Axes>"
      ]
     },
     "metadata": {
      "needs_background": "light"
     },
     "output_type": "display_data"
    }
   ],
   "source": [
    "sli = 35\n",
    "vol = 127\n",
    "orig1 = data[:, :, sli, vol]\n",
    "\n",
    "den1 = denoised_sh_mlp[:, :, sli, vol]\n",
    "rms_diff1 = np.sqrt((orig1 - den1) ** 2)\n",
    "\n",
    "fig, ax = plt.subplots(1, 3, figsize=(30, 30))\n",
    "ax[0].imshow(orig1.T, cmap='gray', origin='lower', interpolation='None')\n",
    "ax[0].set_title('Original')\n",
    "ax[0].set_axis_off()\n",
    "ax[1].imshow(den1.T, cmap='gray', origin='lower', interpolation='None')\n",
    "ax[1].set_title('Patch2Self')\n",
    "ax[1].set_axis_off()\n",
    "ax[2].imshow(rms_diff1.T, cmap='gray', origin='lower', interpolation='None')\n",
    "ax[2].set_title('Residual')\n",
    "ax[2].set_axis_off()\n",
    "plt.show()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "#### We save the denoised output in Nifti file format and will use it in the `Regression_Comparison` notebook"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [],
   "source": [
    "save_nifti('denoised_StanfordHardi_p2s_mlp.nii.gz', denoised_sh, affine)"
   ]
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "Python 3",
   "language": "python",
   "name": "python3"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.7.4"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 2
}