diff --git a/cpp/CMakePresets.json b/cpp/CMakePresets.json
index 13d1241990c31..cb4cdfc03ac82 100644
--- a/cpp/CMakePresets.json
+++ b/cpp/CMakePresets.json
@@ -220,6 +220,14 @@
         "PARQUET_REQUIRE_ENCRYPTION": "ON"
       }
     },
+    {
+      "name": "features-valgrind",
+      "hidden": true,
+      "cacheVariables": {
+        "ARROW_RUNTIME_SIMD_LEVEL": "AVX2",
+        "ARROW_TEST_MEMCHECK": "ON"
+      }
+    },
     {
       "name": "ninja-debug-minimal",
       "inherits": [
@@ -331,6 +339,46 @@
       "displayName": "Debug build with everything enabled (except benchmarks)",
       "cacheVariables": {}
     },
+    {
+      "name": "ninja-debug-valgrind-basic",
+      "inherits": [
+        "base-debug",
+        "features-basic",
+        "features-valgrind"
+      ],
+      "displayName": "Debug build for Valgrind with reduced dependencies",
+      "cacheVariables": {}
+    },
+    {
+      "name": "ninja-debug-valgrind",
+      "inherits": [
+        "base-debug",
+        "features-main",
+        "features-valgrind"
+      ],
+      "displayName": "Debug build for Valgrind with more optional components",
+      "cacheVariables": {}
+    },
+    {
+      "name": "ninja-debug-valgrind-minimal",
+      "inherits": [
+        "base-debug",
+        "features-minimal",
+        "features-valgrind"
+      ],
+      "displayName": "Debug build for Valgrind without anything enabled",
+      "cacheVariables": {}
+    },
+    {
+      "name": "ninja-debug-valgrind-maximal",
+      "inherits": [
+        "base-debug",
+        "features-maximal",
+        "features-valgrind"
+      ],
+      "displayName": "Debug build for Valgrind with everything enabled",
+      "cacheVariables": {}
+    },
     {
       "name": "ninja-release-minimal",
       "inherits": [
@@ -491,4 +539,4 @@
       }
     }
   ]
-}
\ No newline at end of file
+}