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ro.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/ro.owl#"
xml:base="http://purl.obolibrary.org/obo/ro.owl"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
xmlns:swrlb="http://www.w3.org/2003/11/swrlb#"
xmlns:swrl="http://www.w3.org/2003/11/swrl#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:cito="http://purl.org/spar/cito/"
xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:foaf="http://xmlns.com/foaf/0.1/"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/ro.owl">
<owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/ro/releases/2017-07-19/ro.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/annotations.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/pato_import.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/temporal-intervals.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/go_cc_import.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/go_mf_import.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/core.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/rohom.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/go-biotic.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/el-constraints.owl"/>
<dc:description xml:lang="en">The OBO Relations Ontology (RO) is a collection of OWL relations (ObjectProperties) intended for use across a wide variety of biological ontologies.</dc:description>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Includes Ontology(OntologyID(Anonymous-21)) [Axioms: 26 Logical Axioms: 0]</rdfs:comment>
<foaf:homepage rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI"> https://github.com/oborel/obo-relations/</foaf:homepage>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Includes Ontology(OntologyID(Anonymous-21)) [Axioms: 32 Logical Axioms: 0]</rdfs:comment>
<dc:source rdf:resource="http://obofoundry.org/ro"/>
<dc:title xml:lang="en">OBO Relations Ontology</dc:title>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000232 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000232"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000426 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000426">
<obo:IAO_0000115>An assertion that holds between an OWL Object Property and a string or literal, where the value of the string or literal is a Common Logic sentence of collection of sentences that define the Object Property.</obo:IAO_0000115>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/IAO_0000589 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000589">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdfs:label xml:lang="en">OBO foundry unique label</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001900 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001900">
<obo:IAO_0000115>An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.</obo:IAO_0000115>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002161 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002161">
<obo:IAO_0000112>tooth SubClassOf 'never in taxon' value 'Aves'</obo:IAO_0000112>
<obo:IAO_0000115>x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/17921072"/>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20973947"/>
<obo:IAO_0000425>?X DisjointWith RO_0002162 some ?Y </obo:IAO_0000425>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">never in taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002171 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002171">
<obo:IAO_0000115>A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B.</obo:IAO_0000115>
<obo:IAO_0000118>non-overlapping with</obo:IAO_0000118>
<obo:IAO_0000118>shares no parts with</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<obo:IAO_0000425>Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)</obo:IAO_0000425>
<rdfs:label xml:lang="en">mutually spatially disjoint with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/RO_0002163"/>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002172 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002172">
<obo:IAO_0000115>An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon.</obo:IAO_0000115>
<rdfs:label xml:lang="en">taxonomic class assertion</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002173 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002173">
<obo:IAO_0000115>S ambiguous_for_taxon T if the class S does not have a clear referent in taxon T. An example would be the class 'manual digit 1', which encompasses a homology hypotheses that is accepted for some species (e.g. human and mouse), but does not have a clear referent in Aves - the referent is dependent on the hypothesis embraced, and also on the ontogenetic stage. [PHENOSCPAE:asilomar_mtg]</obo:IAO_0000115>
<rdfs:label xml:lang="en">ambiguous for taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002174 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002174">
<obo:IAO_0000115>S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-6601-2165</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<rdfs:comment>This relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take ongoing coordinated effort to resolve. Example: metencephalon in teleost</rdfs:comment>
<rdfs:label xml:lang="en">dubious for taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002175 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002175">
<obo:IAO_0000115>S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-6601-2165</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<rdfs:label xml:lang="en">present in taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002259 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002259">
<rdfs:label>defined by inverse</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SubsetProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002416 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002416">
<obo:IAO_0000115>An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.</obo:IAO_0000115>
<rdfs:label xml:lang="en">logical macro assertion</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/ShortcutRelations</foaf:page>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002419 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002419">
<obo:IAO_0000115>An assertion that holds between an OWL Annotation Property P and a non-negative integer N, with the interpretation: for any P(i j) it must be the case that | { k : P(i k) } | = N.</obo:IAO_0000115>
<rdfs:label xml:lang="en">annotation property cardinality</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002423"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#nonNegativeInteger"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002420 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002420">
<obo:IAO_0000115>A logical macro assertion whose domain is an IRI for a class</obo:IAO_0000115>
<obo:IAO_0000116>The domain for this class can be considered to be owl:Class, but we cannot assert this in OWL2-DL</obo:IAO_0000116>
<rdfs:label xml:lang="en">logical macro assertion on a class</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002421 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002421">
<obo:IAO_0000115>A logical macro assertion whose domain is an IRI for a property</obo:IAO_0000115>
<rdfs:label xml:lang="en">logical macro assertion on a property</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002422 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002422">
<rdfs:label xml:lang="en">logical macro assertion on an object property</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002421"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002423 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002423">
<rdfs:label xml:lang="en">logical macro assertion on an annotation property</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002421"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002474 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002474">
<obo:IAO_0000115>An assertion that holds between an OWL Object Property and a dispositional interpretation that elucidates how OWL Class Axioms or OWL Individuals that use this property are to be interpreted in a dispositional context. For example, A binds B may be interpreted as A have a mutual disposition that is realized by binding to the other one.</obo:IAO_0000115>
<rdfs:label>dispositional interpretation</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002475 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002475">
<obo:IAO_0000112>'pectoral appendage skeleton' has no connections with 'pelvic appendage skeleton'</obo:IAO_0000112>
<obo:IAO_0000115>A is has_no_connections_with B if there are no parts of A or B that have a connection with the other.</obo:IAO_0000115>
<obo:IAO_0000118>shares no connection with</obo:IAO_0000118>
<obo:IAO_0000425>Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (RO_0002170 some (BFO_0000050 some ?Y))</obo:IAO_0000425>
<rdfs:label>has no connections with</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002483 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002483">
<rdfs:label>inherited annotation property</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002484 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002484">
<obo:IAO_0000115>Connects an ontology entity (class, property, etc) to a URL from which curator guidance can be obtained. This assertion is inherited in the same manner as functional annotations (e.g. for GO, over SubClassOf and part_of)</obo:IAO_0000115>
<rdfs:label>curator guidance link</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002483"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002504 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002504">
<obo:IAO_0000112>brain always_present_in_taxon 'Vertebrata'</obo:IAO_0000112>
<obo:IAO_0000112>forelimb always_present_in_taxon Euarchontoglires</obo:IAO_0000112>
<obo:IAO_0000115>S always_present_in_taxon T if every fully formed member of taxon T has part some S, or is an instance of S</obo:IAO_0000115>
<obo:IAO_0000116>This is a very strong relation. Often we will not have enough evidence to know for sure that there are no species within a lineage that lack the structure - loss is common in evolution. However, there are some statements we can make with confidence - no vertebrate lineage could persist without a brain or a heart. All primates are limbed. </obo:IAO_0000116>
<obo:IAO_0000118>never lost in</obo:IAO_0000118>
<rdfs:label>always present in taxon</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002175"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002535 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002535">
<obo:IAO_0000232>This properties were created originally for the annotation of developmental or life cycle stages, such as for example Carnegie Stage 20 in humans. </obo:IAO_0000232>
<rdfs:label>temporal logical macro assertion on a class</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002536 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002536">
<rdfs:label>measurement property has unit</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002423"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002537 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002537">
<rdfs:label>has start time value</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002538 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002538">
<rdfs:label>has end time value</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002539 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002539">
<obo:IAO_0000115>Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property.</obo:IAO_0000115>
<rdfs:label>start, days post fertilization</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002540 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002540">
<obo:IAO_0000115>Count of number of days intervening between the end of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 1 for this property.</obo:IAO_0000115>
<rdfs:label>end, days post fertilization</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002541 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002541">
<obo:IAO_0000115>Count of number of years intervening between the start of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 0 for this property, and the period during which the child is one year old has the value 1.</obo:IAO_0000115>
<rdfs:label>start, years post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002542 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002542">
<obo:IAO_0000115>Count of number of years intervening between the end of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 1 for this property, and the period during which the child is one year old has the value 2</obo:IAO_0000115>
<rdfs:label>end, years post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002543 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002543">
<obo:IAO_0000115>Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the child is one month old has the value 1.</obo:IAO_0000115>
<rdfs:label>start, months post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002544 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002544">
<obo:IAO_0000115>Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the child is one month old has the value 2</obo:IAO_0000115>
<rdfs:label>end, months post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002545 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002545">
<obo:IAO_0000115>Defines the start and end of a stage with a duration of 1 month, relative to either the time of fertilization or last menstrual period of the mother (to be clarified), counting from one, in terms of a reference model. Thus if month_of_gestation=3, then the stage is 2 month in.</obo:IAO_0000115>
<rdfs:label>month of gestation</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002546 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002546">
<obo:IAO_0000115>A relationship between a stage class and an anatomical structure or developmental process class, in which the stage is characterized by the appearance of the structure or the occurrence of the biological process</obo:IAO_0000115>
<rdfs:label>has developmental stage marker</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002547 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002547">
<obo:IAO_0000115>Count of number of days intervening between the start of the stage and the time of coitum.</obo:IAO_0000115>
<obo:IAO_0000232>For mouse staging: assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)</obo:IAO_0000232>
<rdfs:label>start, days post coitum</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002548 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002548">
<obo:IAO_0000115>Count of number of days intervening between the end of the stage and the time of coitum.</obo:IAO_0000115>
<rdfs:label>end, days post coitum</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002549 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002549">
<rdfs:label>start, weeks post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002550 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002550">
<rdfs:label>end, weeks post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002560 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002560">
<obo:IAO_0000115>If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x subject-partner-in p, y object-partner-in p</obo:IAO_0000115>
<rdfs:label>is asymmetric relational form of process class</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002562"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002561 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002561">
<obo:IAO_0000115>If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x partner-in p, y partner-in p</obo:IAO_0000115>
<rdfs:label>is symmetric relational form of process class</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002562"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002562 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002562">
<obo:IAO_0000115>R is the relational form of a process if and only if either (1) R is the symmetric relational form of a process or (2) R is the asymmetric relational form of a process</obo:IAO_0000115>
<rdfs:label>is relational form of process class</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002594"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002575 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002575">
<obo:IAO_0000115>relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y</obo:IAO_0000115>
<obo:IAO_0000116>The general property hierarchy is:
"directly P" SubPropertyOf "P"
Transitive(P)
Where we have an annotation assertion
"directly P" "is direct form of" "P"</obo:IAO_0000116>
<obo:RO_0002423>If we have the annotation P is-direct-form-of Q, and we have inverses P' and Q', then it follows that P' is-direct-form-of Q'</obo:RO_0002423>
<dc:creator>Chris Mungall</dc:creator>
<rdfs:label>is direct form of</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002579 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002579">
<obo:IAO_0000115>relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y</obo:IAO_0000115>
<dc:creator>Chris Mungall</dc:creator>
<rdfs:label>is indirect form of</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002580 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002580">
<rdfs:label>logical macro assertion on an axiom</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002581 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002581">
<obo:IAO_0000115>If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL</obo:IAO_0000115>
<rdfs:label>is a defining property chain axiom</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002580"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002582 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002582">
<obo:IAO_0000115>If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.</obo:IAO_0000115>
<rdfs:label>is a defining property chain axiom where second argument is reflexive</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002581"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002594 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002594">
<obo:IAO_0000115>An annotation property that connects an object property to a class, where the object property is derived from or a shortcut property for the class. The exact semantics of this annotation may vary on a case by case basis.</obo:IAO_0000115>
<rdfs:label>is relational form of a class</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002601 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002601">
<obo:IAO_0000115>A shortcut relationship that holds between two entities based on their identity criteria</obo:IAO_0000115>
<rdfs:label>logical macro assertion involving identity</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002602 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002602">
<obo:IAO_0000115>A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds.</obo:IAO_0000115>
<rdfs:label>in approximate one to one relationship with</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002601"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002603 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002603">
<obo:IAO_0000115>x is approximately equivalent to y if it is the case that x is equivalent, identical or near-equivalent to y</obo:IAO_0000115>
<obo:IAO_0000232>The precise meaning of this property is dependent upon some contexts. It is intended to group multiple possible formalisms. Possibilities include a probabilistic interpretation, for example, Pr(x=y) > 0.95. Other possibilities include reified statements of belief, for example, "Database D states that x=y"</obo:IAO_0000232>
<rdfs:label>is approximately equivalent to</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002602"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002604 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002604">
<obo:IAO_0000112>'anterior end of organism' is-opposite-of 'posterior end of organism'</obo:IAO_0000112>
<obo:IAO_0000112>'increase in temperature' is-opposite-of 'decrease in temperature'</obo:IAO_0000112>
<obo:IAO_0000115>x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).</obo:IAO_0000115>
<rdfs:label>is opposite of</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002602"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002605 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002605">
<obo:IAO_0000115>x is indistinguishable from y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).</obo:IAO_0000115>
<rdfs:label>is indistinguishable from</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002603"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002611 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002611">
<rdfs:label>evidential logical macro assertion on an axiom</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002580"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002612 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002612">
<obo:IAO_0000115>A relationship between a sentence and an instance of a piece of evidence in which the evidence supports the axiom</obo:IAO_0000115>
<obo:IAO_0000232>This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual.</obo:IAO_0000232>
<rdfs:label>axiom has evidence</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002611"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002613 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002613">
<obo:IAO_0000115>A relationship between a sentence and an instance of a piece of evidence in which the evidence contradicts the axiom</obo:IAO_0000115>
<obo:IAO_0000232>This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual.</obo:IAO_0000232>
<rdfs:label>axiom contradicted by evidence</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002611"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002617 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002617">
<obo:IAO_0000112>In the context of a particular project, the IRI with CURIE NCBIGene:64327 (which in this example denotes a class) is considered to be representative. This means that if we have equivalent classes with IRIs OMIM:605522, ENSEMBL:ENSG00000105983, HGNC:13243 forming an equivalence set, the NCBIGene is considered the representative member IRI. Depending on the policies of the project, the classes may be merged, or the NCBIGene IRI may be chosen as the default in a user interface context.</obo:IAO_0000112>
<obo:IAO_0000115>this property relates an IRI to the xsd boolean value "True" if the IRI is intended to be the representative IRI for a collection of classes that are mutually equivalent.</obo:IAO_0000115>
<obo:IAO_0000232>If it is necessary to make the context explicit, an axiom annotation can be added to the annotation assertion</obo:IAO_0000232>
<rdfs:label>is representative IRI for equivalence set</rdfs:label>
<rdfs:seeAlso>OWLAPI Reasoner documentation for representativeElement, which follows a similar idea, but selects an arbitrary member</rdfs:seeAlso>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002601"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/ro/subsets#ro-eco -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ro/subsets#ro-eco">
<rdfs:label>eco subset</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SubsetProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/description -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description"/>
<!-- http://purl.org/spar/cito/citesAsAuthority -->
<owl:AnnotationProperty rdf:about="http://purl.org/spar/cito/citesAsAuthority"/>
<!-- http://swrl.stanford.edu/ontologies/3.3/swrla.owl#isRuleEnabled -->
<owl:AnnotationProperty rdf:about="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#isRuleEnabled"/>
<!-- http://www.geneontology.org/formats/oboInOwl#SubsetProperty -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#SubsetProperty">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">subset_property</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#created_by -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#created_by"/>
<!-- http://www.geneontology.org/formats/oboInOwl#creation_date -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
<!-- http://www.geneontology.org/formats/oboInOwl#inSubset -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">in_subset</rdfs:label>
</owl:AnnotationProperty>
<!-- http://xmlns.com/foaf/0.1/page -->
<owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/page"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/BFO_0000050 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"/>
<rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Submissions:PartOf"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000051 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000062 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062"/>
</owl:propertyChainAxiom>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/BFO_0000063 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002092"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
</owl:propertyChainAxiom>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/R0_0009004 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/R0_0009004">
<obo:IAO_0000112 xml:lang="en">sardine has consumer some homo sapiens</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">'has consumer' is a relation between a material entity and an organism in which the former can normally be digested or otherwise absorbed by the latter without immediate or persistent ill effect.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<rdfs:label xml:lang="en">has consumer</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000052 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002314"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0000057 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000057">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000055"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000052"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000057"/>
</owl:propertyChainAxiom>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0000300 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000300">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A relation that holds between two neurons connected directly via a synapse, or indirectly via a series of synaptically connected neurons.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(or
(synapsed_by ?x ?y)
(synapsed_to ?x ?y)))))
(forall (...s ?x ?y ?z)
(iff
(neural_circuit_path ...s ?x ?y ?z)
(and
(neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(or
(synapsed_by ?y ?z)
(synapsed_to ?y ?z)))))
(forall (?x ?y)
(iff
(in_neural_circuit_with ?x ?y)
(exists (...s)
(neural_circuit_path ?x ...s ?y)))) </obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">in neural circuit with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000301 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000301">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000300"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A relation that holds between a neuron that is synapsed_to another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_to the next.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(upstream_neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(synapsed_to ?x ?y))))
(forall (...s ?x ?y ?z)
(iff
(upstream_neural_circuit_path ...s ?x ?y ?z )
(and
(upstream_neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(synapsed_to ?y ?z))))
(forall (?x ?y)
(iff
(upstream_in_neural_circuit_with ?x ?y)
(exists (...s)
(upstream_neural_circuit_path ?x ...s ?y))))</obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">upstream in neural circuit with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000302 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000302">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000300"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A relation that holds between a neuron that is synapsed_to another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_to the next.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(downstream_neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(synapsed_by ?x ?y))))
(forall (...s ?x ?y ?z)
(iff
(downstream_neural_circuit_path ...s ?x ?y ?z )
(and
(downstream_neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(synapsed_by ?y ?z))))
(forall (?x ?y)
(iff
(downstream_in_neural_circuit_with ?x ?y)
(exists (...s)
(downstream_neural_circuit_path ?x ...s ?y))))
</obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">downstream in neural circuit with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001018 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001018">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001019"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001025"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000111 xml:lang="en">contained in</obo:IAO_0000111>
<obo:IAO_0000116>Containment is location not involving parthood, and arises only where some immaterial continuant is involved.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Intended meaning:
domain: material entity
range: spatial region or site (immaterial continuant)
</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">contained_in</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">contained in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001019 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001019">
<obo:IAO_0000111 xml:lang="en">contains</obo:IAO_0000111>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">contains</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001020 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001020">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001022"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000112>penicillin (CHEBI:17334) is allergic trigger for penicillin allergy (DOID:0060520)</obo:IAO_0000112>
<obo:IAO_0000115>A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">is allergic trigger for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001021 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001021">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001023"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">is autoimmune trigger for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001022 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001022">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000112>penicillin allergy (DOID:0060520) has allergic trigger penicillin (CHEBI:17334)</obo:IAO_0000112>
<obo:IAO_0000115>A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">has allergic trigger</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001023 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001023">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">has autoimmune trigger</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002000 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002000">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>