diff --git a/episodes/04-which-cloud.md b/episodes/04-which-cloud.md
index 42b2ddd1..52d403ce 100644
--- a/episodes/04-which-cloud.md
+++ b/episodes/04-which-cloud.md
@@ -181,6 +181,21 @@ my university HPCC for running the full dataset.
 > - How many times will you need to run this pipeline?
 {: .challenge}
 
+> ## Human genomic data & Security
+> 
+> Note that if you are working with human genomics data there might be ethical and legal 
+> considerations that affect your choice of cloud resources to use. The terms of use, and/or 
+> the legislation under which you are handling the genomic data, might impose heightened information 
+> security measures for the computing environment in which you intend to process it. This is a too broad 
+> topic to discuss in detail here, but in general terms you should think through the technical and 
+> procedural measures needed to ensure that the confidentiality and integrity of the human data you work 
+> with is not breached. If there are laws that govern these issues in the jurisdiction in which you work, 
+> be sure that the cloud service provider you use can certify that they support the necessary measures. 
+> Also note that there might exist restrictions for use of cloud service providers that operate in other 
+> jurisdictions than your own, either by how the data was consented by the research subjects or by the 
+> jurisdiction under which you operate. Do consult the legal office of your institution for guidance 
+> when processing human genomic data.
+{: .callout}
 
 ### Other Resources: