diff --git a/data/2024/2024-09-11/readme.md b/data/2024/2024-09-11/readme.md new file mode 100644 index 0000000..e142d2d --- /dev/null +++ b/data/2024/2024-09-11/readme.md @@ -0,0 +1,36 @@ +Personalized dosing +=================== + +## Background + +Why personalized dosing? + +„Again and again, it has been shown that certain patients benefit more from individual drugs, +while others suffer more heavily from side effects… +…and still they are usually treated with a standard dose." +Free translation of a quote from Prof. Dr. Dr. Gerd Geisslinger, Executive Director, +Fraunhofer Institute for Translational Medicine and Pharmacology, Frankfurt + +## Data set + +A simulated dose response [data set](WWW54ExampleData.csv) + +* dose: dose levels (0, 100, 200 mg) +* target: continuous response variable (higher is better) +* subgroup variables: + + bmi (body mass index: ‘low BMI’ or ‘high BMI’) + + age (‘<40 years’ or ‘≥40 years’) + + race (‘Black’, ‘Asian’, ‘White’) + + sex (‘Female’, ‘Male’) + + type (type of disease: ‘Acute disease’ or ‘Chronic disease’) + + +## The Challenge + +Aim of the visualisation + +* Identify subgroups with a dose response that deviates from the remaining study participants +* Therewith potential subgroups for personalized dosing could be identified + + +