- Cluster split samples together in DADA2
- updated all packages except SWARM
- Updated Snakemake version
- Changed RAM usage of DADA2 by running clustering on single samples, while still estimating errors on all samples.
- updated to NCBI version 5 BLAST databases (dbV5) which require different files and BLAST+ > 2.9.0
- changed SILVA rules accordingly to work with new BLAST
- older NCBI database versions will no longer be supported (v4 soon depricated at NCBI)
- Added support for amplicon sequence variants using the DADA2 algorithm
- Added more logging information